For modeling cell growth and behavior in the body, scientists are turning to three-dimensional culture systems that create more lifelike environs
According to Zhang, the shift toward 3-D scaffolding systems is essential to keep researchers from "barking up the wrong tree" by chasing targets that reflect a cell's mutated behavior under two-dimensional systems. "I tell the people," Zhang says, "that probably in 20 years, all the textbooks concerning tissue culture will have to be revised because of these 3-D cell culture systems."
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