The positive effects of TMS are intriguing. In 1999 Ehud Klein, a psychologist at the Rambam Medical Center in Haifa, Israel, led the largest study to date. Klein exposed 70 patients suffering from major depression to 10 daily sessions of repetitive TMS over a two-week period. Half received real TMS, and half received a sham version--the magnet was held at an angle that rendered the field ineffective. The mood of participants who had been properly exposed improved on the Hamilton Depression Rating Scale, used to assess symptoms. But no change was found for subjects who had sat under the ineffective coils.
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