Cover Image: August 2003 Scientific American Magazine See Inside

Censors of the Genome [Preview]

Biologists have been surprised to discover that most animal and plant cells contain a built-in system to silence individual genes by shredding the RNA they produce. Biotech companies are already working to exploit it















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Observed on a microscope slide, a living cell appears serene. But underneath its tranquil facade, it buzzes with biochemical chatter. The DNA genome inside every cell of a plant or animal contains many thousands of genes. Left to its own devices,

the transcription machinery of the cell would express every gene in the genome at once: unwinding the DNA double helix, transcribing each gene into single-stranded messenger RNA and, finally, translating the RNA messages into their protein forms.


This article was originally published with the title Censors of the Genome.



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