But other scientists argue that endocrine disruptors have ‘low-dose effects’, meaning the classic linear relationship between dose and response is altered and very small amounts can actually have a greater impact than higher amounts.
In response to the editorial by Dietrich and his colleagues, 41 scientists published their own commentary in Environmental Health in August. The authors wrote that the July editorial “confuses and conflates several aspects of the current debate” and noted that “the existence of a threshold for endocrine disruptors … remains under debate”.
Others supported Dietrich et al. An editorial in Toxicological Science published 5 September approvingly cites their piece while criticizing toxicologists for being “mostly bystanders” in debates on safety.
Gore says that it is vital that the two communities work together on the issue. But, she admits: “It’s hard to imagine these two groups sitting down and having a pleasant conversation.”