Some researchers still argue, however, that attenuated psychosis syndrome is useful and that further research will support its utility. "I think it is the future of therapeutics and our best hope to make a real-life course difference for people vulnerable to developing chronic psychosis," William Carpenter, director of the Maryland Psychiatric Research Center, wrote in an e-mail. "I would have preferred to place it in the main text now, but appreciate the limitation without proof of good reliability." Patrick McGorry, director of the Orygen Youth Health Research Center in Australia, has similar thoughts. "On balance, I agree with and can certainly accept the decision," he said in an e-mail. McGorry notes, however, that although only one third of children identified as high risk for psychosis become psychotic, more than 70 percent of the remaining children develop mood, anxiety or substance use disorders, according to data he has presented at conferences and will publish shortly. Both Carpenter and McGorry say that antipsychotics and other drugs are not the only treatment option; alternatives include cognitive behavioral therapy to recognize and diminish maladaptive thought patterns, talk therapy, interventions to reduce substance abuse and simply increased watchfulness for any worsening indicators of psychosis.