For his part, Sinclair is eager to see the results of his experiments with the supermouse. "Depending on how this mouse turns out," he says, "we may put NAMPT on the list of drug targets, as well."

5 Comments

1. 1. Dr B Ravinder Reddy 01:53 PM 3/6/08

   Eating less probably increases our life span! In persons who are critically ill, it has now been shown that under-feeding such seriously sick patients will increase the chances of their survival! The mechanisms involved are probably more than one! And eating less has many other advantages than increasing the longivity!

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2. 2. concon 02:29 PM 3/24/09

   i was wondering what do or can i eat for Eat (Less) to Live (Longer) issue i am 47 cant stop gaining weight ..high blood pressure .heart disease runs in family//the list goes on i would really like to start living i have 2 bad knees they just cripple me some days and full of arthitics would love to play with grand babies etc ..and my grandparents dies in their 60s
   thank you connie fallon

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3. 3. concon 03:44 PM 3/24/09

   sorry my typing is so messy and miss spelled i was upset while i was writing please help me

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4. 4. Dr. Farr in reply to concon 12:48 PM 4/1/09

   Connie, it's a long haul, but you can do it. You'll need some self-discipline. First, learn the difference between nutritious food and the foods you crave. A good clue is to eat things that are still living: carrots, apples, spinach, etc. and avoid things that are long dead: flour, milk, butter, cheese, etc. and religiously avoid industrial and fast "foods:" pizza, fried chicken, hamburgers, french fries, macaroni, etc. I'll bet money that the foods you love most are the worst for you. If you stop eating for flavor alone and don't use food for "comfort," that is eat when you're upset, you'll automatically begin to lose weight and regain your health. After awhile, six months to a year, you won't need discipline because your body will develop a taste for healthy eating. After that, it will be easy.

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5. 5. Dr. Farr in reply to concon 12:50 PM 4/1/09

   Connie, it's a long haul, but you can do it. You'll need some self-discipline. First, learn the difference between nutritious food and the foods you crave. A good clue is to eat things that are still living: carrots, apples, spinach, etc. and avoid things that are long dead: flour, milk, butter, cheese, etc. and religiously avoid industrial and fast "foods:" pizza, fried chicken, hamburgers, french fries, macaroni, etc. I'll bet money that the foods you love most are the worst for you. If you stop eating for flavor alone and don't use food for "comfort," that is eat when you're upset, you'll automatically begin to lose weight and regain your health. After awhile, six months to a year, you won't need discipline because your body will develop a taste for healthy eating. After that, it will be easy.

   Reply | Report Abuse | Link to this