How does catnip work its magic on cats?















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Ramona Turner, a veterinarian specializing in feline care for 25 years, owns two Fresno, Ca.–based animal hospitals. She answers this riddle about our furry friends' strange behavior.

Cats, from our domestic companions to lions and tigers, are exquisitely susceptible to a volatile oil found in the stems and leaves of the catnip plant.

When cats smell catnip they exhibit several behaviors common to queens in season (females in heat): They may rub their heads and body on the herb or jump, roll around, vocalize and salivate. This response lasts for about 10 minutes, after which the cat becomes temporarily immune to catnip's effects for roughly 30 minutes. Response to catnip is hereditary; about 70 to 80 percent of cats exhibit this behavior in the plant's presence. In addition, catnip does not affect kittens until they are about six months old and begin to reach sexual maturity.

Catnip plants (Nepeta cataria and other Nepeta species) are members of the mint family and contain volatile oils, sterols, acids and tannins. Native to Europe, Asia and Africa, the plant was brought to North America by settlers; nowadays, the plant is popular in herb gardens and grows widely as a weed. Catnip is considered to be nonaddictive and completely harmless to cats.

So, how does catnip work? Nepetalactone, one of catnip's volatile oils, enters the cat's nasal tissue, where it is believed to bind to protein receptors that stimulate sensory neurons. These cells, in turn, provoke a response in neurons in the olfactory bulb, which project to several brain regions including the amygdala (two neuronal clusters* in the midbrain that mediate emotional responses to stimuli) and the hypothalamus, the brain's "master gland" that plays a role in regulating everything from hunger to emotions.

The amygdala integrates the information flow from the olfactory bulb cells and projects to areas governing behavior responses. The hypothalamus regulates neuroendocrine responses through the pituitary gland, creating a "sexual response." That is, the cat essentially reacts to an artificial cat pheromone.

Human brains are physiologically different from cat brains and people do not react to catnip by getting "high." Native Americans, however, once used catnip for the uncontrollable cries of infant colic. It also serves as a mild sedative in some herbal teas. In alternative medicine circles, catnip is commonly recommended by herbalists to lessen migraine headaches and to relieve cramps, gas, indigestion, insomnia, nervousness and anorexia, or as an herbal paste to reduce swelling associated with arthritis and soft tissue injury.

*CORRECTION: Initially, this phrase read "two almond-size neuronal clusters in the midbrain..." Almond-size refers to the amygdala in humans, not cats.



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  1. 1. kakskee 03:05 AM 2/18/08

    I wonder if a person with a substance addiction had a cat gene spliced into their body, would a catnip fix alleviate.the craving for the drug or alcohol fix?

    Reply | Report Abuse | Link to this
  2. 2. cransona in reply to kakskee 04:12 PM 6/26/09

    Why not just splice-out the addiction gene? Sounds just as reasonable... *chuckle*

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  3. 3. tinkerbell1 12:18 PM 2/4/10

    No and your deffinatly not gonna get the same results. and I'm pretty sure humans don't have cat genes. *hehe*

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  4. 4. Anonymouse.Na 07:19 AM 3/16/10

    as there are only a few animals mainly mammals that reproduce for pleasure, are felines another species that does this too? i watched an episode of south park and there was catnip in a box that made cartmans cat very horny, so horny it invited the entire neighborhood over for a cat orgy. I have also experimented by using on a cat and it did everything as above, she was female but there werent any males around so I cant conclude anything. I even smoked the catnip to find out what happens but the answer still didnt make sense. you sound smart, so is this an aphrodisiac for pleasure of male and female cats?
    -anonymouse.

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  5. 5. Jason Hops 05:36 AM 5/17/13

    Flooding ALL White countries and ONLY White countries with non-Whites and then forcing assimilation is a program of White genocide.

    Africa will still be full of Africans
    Asia will still be full of Asians.
    Only White children will suffer from this.

    Read the UN genocide conventions: It is genocide, White Genocide.

    They say they are anti-racist. What they are is anti-White.
    Anti-racist is a code word for anti-White.

    Reply | Report Abuse | Link to this
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