Fasting Might Boost Chemo's Cancer-Busting Properties

A new animal study suggests that short-term starvation might improve outcomes for cancer patients undergoing chemotherapy















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But the results from human trials are not conclusive yet, and Barcellos-Hoff emphasizes that even if it has looked promising in mouse studies, fasting alone (without chemotherapy) should not be something patients attempt on their own. Especially for a patient who already has decent odds of survival, undertaking an unproved approach can be quite risky.

And although many diets and alternative treatment regimens exist, Longo cautions, "if you do it without the science, you can end up doing more damage than good." For example, when a fast is too long the immune system starts to suffer, potentially leaving a patient even less protected.

"Everything has to be timed so that it maximizes the damage to the cancer," he says. Research into that is still ongoing. Even just finding out whether fasting with chemo will be as successful in humans as it is in mice might not come quickly. "You have so many cancers and so many chemos that it's almost like a never-ending process," Longo says.



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  1. 1. cdmgsdad 05:42 PM 2/8/12

    Do you suppose it took FIVE YEARS of "studies" to come up with this--because they cannot CHARGE people not to be fed?

    In the meantime, how many people have been burned, cut apart and chemically poisoned to an unnecessary degree by their primitive medical methods--when some SIMPLE procedure would have greatly mitigated so much suffering, with so little effort?

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  2. 2. AzraCosta in reply to cdmgsdad 05:57 PM 2/8/12

    *boosts chemo's cancer-busting properties*, not *cures cancer on it's own*. C'mon it's right in the headline!

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  3. 3. cdmgsdad in reply to AzraCosta 06:36 PM 2/8/12

    I am not advocating no treatment except fasting.

    But it should be obvious that implementing this SIMPLE procedure early on would certainly have been a logical and low risk method of enhancing treatment.

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  4. 4. rgcorrgk 08:16 PM 2/8/12

    Dear Katherine Harmon thanks for a thoughtful report. It is odd to me that this area of research seems so undeveloped given how seemingly basic it appears. True, "promising cures" come and go; but, the depth of type & magnitude of effect seen, even given mouse cancer, would seem highly likely to portend effective fasting-chemotherapy protocols.

    Richard Carlson.

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  5. 5. joshnl in reply to cdmgsdad 08:21 PM 2/8/12

    It's not obvious at all. As was pointed out in the article, there are potential downsides (including dangerous ones) to fasting, and it is unclear if the POSSIBLE benefits of fasting during chemo will outweigh the downsides.

    An important principle to follow in science and medicine is not to jump to conclusions based on preliminary data. Having said that, in the case of patients undergoing chemo, a supplementary treatment that may have positive effects (which have not yet been proven) couldn't hurt and may be a good thing, ASSUMING THERE WERE NO RISKS ASSOCIATED WITH THE SUPPLEMENTAL TREATMENT. But in this case, there are. Aside from the obvious side effects, for all anyone knows, in humans, fasting may give cancer cells a foothold and WORSEN patient outcome.

    So I'm not sure what the point is of jumping to the implied conclusion that some grand conspiracy has resulted in the idea of fasting to help cancer patients being suppressed for years.

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  6. 6. cdmgsdad in reply to joshnl 09:14 PM 2/8/12

    As the article says--fasting has been a historical part of human society for ages.

    Determining that there are/or are not complications that are WORSE than the VERY SUBSTANCIAL unmitigated side effects of Chemo, X-rays, or surgery--should not take over FIVE YEARS (as the article says).

    Have you, or any of your family actually been through any of the modern medical horrors that are side effects of cancer treatment?

    All effort should be made to lessen these effects--

    I cannot say that these facts have been "suppressed for years"--But it has been commonly available information that has not been acted of for years-- note this from 2008:

    http://www.physorg.com/news126202490.html

    The snail's pace of progress is inexcusable.

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  7. 7. joshnl in reply to cdmgsdad 09:35 PM 2/8/12

    As a matter of fact, my mother is currently undergoing chemo; so yes, I am familiar with the fact that chemo is not a particularly pleasant experience. But that isn't the issue here. It's not chemo vs. something else; it's chemo alone or chemo in conjunction with something else.

    I work day in and day out researching the new and cutting edge ways to treat and diagnose cancer and other diseases. This involves working with university researchers. I have also been a researcher myself. So I can assure you that researchers are trying to move their work forward as quickly as they possibly can. There are a number of factors which contribute to slowing down work. Some examples include: (1) the nature of proper scientific research -namely it being a painfully slow process; (2) a serious lack of funding, and the fact that researchers have to spend inordinate amounts of time trying to get funding; (3) obstacles around clinical trials, including strict ethical guidelines which must be carefully navigated, and which lead to it taking a long time to get enough data to convincingly support a particular conclusion.

    You say that the snail's pace of progress is inexcusable. But who are you not excusing? The scientists? Scientists are not perfect - trust me - I used to be one; but they do a pretty darned good job overall. Doctors? GOOD doctors can only go off what they have to work with: proper evidence from scientists that a particular treatment works safely and effectively. Industry? Industry is far from perfect, but I don't think it's reasonable to think they have control over Joe Blow scientist doing research on the effects of fasting on chemo. I personally think that politicians and the general public need to educate themselves more on all these matters, and contribute more by facilitating increased rates of innovation by the innovators (scientists).

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  8. 8. cdmgsdad in reply to joshnl 10:44 PM 2/8/12

    My experience is that if research is submitted from unexpected areas or from areas outside the usual domain or field of speciality--a great deal of time is wasted in petty arguments by academics,(largely over "turf").

    This is what I should blame for a large portion of the "snails pace".

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  9. 9. ASHIK 10:38 AM 2/9/12

    I did not have any kind of cancer till now.I will do anything to get it completely cured permanently,if i would have it.Unwillingly i am ready to take any kind of pain.Ultimately curse of diseases must get cured.

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  10. 10. Quinlan 04:19 PM 11/17/12

    I'm a breast cancer survivor Her2+++ and I confirm that fasting is a good thing to do. Thanks to fasting, I survived my Chemotherapy. I had no side effects during my chimo, and I felt pretty good! I do thank Dr Valter Longo so much. I was about to start my chemotherapy when I read his research and I decided to fast. I also cut out definitely sugar, coffee and all dairy products.

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  11. 11. wawaju04976 08:44 AM 12/12/12

    I have read quite a bit on fasting prior to chemo. I start my chemo Friday. So, I am going to start my fast at 10 a.m. today. My question...I start chemo at 10 a.m. Friday, and they send me home w/a pump for 48 hours. Should I fast during that time and a bit after when they unplug the pump? I have colon cancer w/mets to the liver and I wanna do anything to help the good cells, anything to kill the bad.

    Thanks,
    Judy

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