Ask anybody what the physical world is made of, and you are likely to be told "matter and energy."
Yet if we have learned anything from engineering, biology and physics, information is just as crucial an ingredient. The robot at the automobile factory is supplied with metal and plastic but can make nothing useful without copious instructions telling it which part to weld to what and so on. A ribosome in a cell in your body is supplied with amino acid building blocks and is powered by energy released by the conversion of ATP to ADP, but it can synthesize no proteins without the information brought to it from the DNA in the cell's nucleus. Likewise, a century of developments in physics has taught us that information is a crucial player in physical systems and processes. Indeed, a current trend, initiated by John A. Wheeler of Princeton University, is to regard the physical world as made of information, with energy and matter as incidentals.
This article was originally published with the title Information in the Holographic Universe.