EVERYBODY HAS THE RIGHT to change his or her mind. But what if the subject of change is not the mind but the brain? This thought, explored in the September 2003 single-topic issue "Better Brains," stirred a gale-force gust of letters from readers. Some were thrilled about the new possibilities for treating neurological diseases. But the moral gray area of gray matter alteration also inspired some consternation and even urgency. Several readers questioned the true impetus behind the lucrative business of brain improvement. Others raised concerns about the physiological and ethical hazards of trying to improve brains that are not actually "broken." These ideas and more fill the following pages.

This article was originally published with the title Letters.

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