Rise in Malaria Rates, Drug Resistance Tied to Climate

At AAAS, a researcher describes how treating more people for the mosquito-borne parasite could lead to more resistance to drugs















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A pregnant woman, with her relative keeping her breathing, is dying of a malaria crisis at the Birao's hospital, northeastern Central African Republic. She will die seven hours later. Image: HDPTCAR VIA FLICKR

CHICAGO—Warmer temperatures are at least partly to blame for a surge in malaria in East Africa and the increase in drug-resistant strains of the disease, according to a University of Michigan researcher.

The malaria parasite is highly sensitive to changes in temperature, and even subtle warming can dramatically increase populations of the mosquitoes that transmit the disease, said ecologist Mercedes Pascual.

Some scientists have argued that climate is not involved in the increasing highland epidemics. Instead, they say, adaptations in the parasite that make it resistant to antimalarial drugs are the key drivers.

But Pascual said that this "either-or" view is misguided and improperly lets global warming off the hook.

"I think that’s a useless discussion," she said.

More likely, Pascual said, the two work in tandem to an effect greater than the sum of their parts, with rising temperatures leading to faster development of drug resistance.

"The literature has this controversy of 'Is it climate or is it drug resistance?' and drug resistance is taken as evidence that we don’t need to invoke climate change," she added.

No research has shown this synergy, but Pascual said it makes theoretical sense.

By making conditions favorable for mosquitoes, "warmer temperatures increase transmission, so you’re going to increase the number of people you treat," she said.  And past research has shown a threshold at which treating more cases leads to a higher incidence of drug resistance, making the disease difficult to treat and contain.

Malaria kills 3,000 people each day in Africa, and outbreaks on the continent aren't limited to the eastern highlands. Climate change will cause the disease to migrate away from low latitudes, scientists say.  That could rid some areas of outbreaks, but could cause others in regions whose inhabitants haven't developed any immunity.

The specifics of how malaria's climate-forced migration will affect outbreaks are largely unknown, but it's already underway, said Christopher Thomas of Aberystwyth University in the U.K.

"It’s now," he said.  "The change isn’t coming at the end of the century—it's happening right now."

Douglas Fischer is editor of The Daily Climate. This article originally appeared at The Daily Climate, the climate change news source published by Environmental Health Sciences, a nonprofit media company.

 



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  1. 1. pgtruspace 11:58 PM 2/16/09

    Let me get this straight. Increase of malaria is caused by Global Warming. I thought it was caused by poor conditions of water management and health care. 200 years ago (a cold period) malaria was endemic in western europe and in the damper areas of eastern & southern united states. Vector control is the best way to control malaria. Global Warming. has nothing to do with it. Cleptocracies that impoverish their populations is the only cause of malarial increase.

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  2. 2. SciGuy 09:55 AM 2/17/09

    SciAm is showing it's Global Warming alarmist bias with this ridiculous article. If anyone dares suggest it is anything but global warming, Pascual merely dismisses it by proclaiming "I think thats a useless discussion." Well then, I guess it's settled and no need for any more actual scientific inquiry, especially since "No research has shown this synergy, but Pascual said it makes theoretical sense." Ok, where again is the SCIENCE to back up this ridiculous claim? Oh right, the "specifics...are largely unknown" but somehow we "know" its already underway. Am I the only one who thinks this is just more of the same Global Warming alarmist propoganda?

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  3. 3. KJeroH 10:32 AM 2/17/09

    It's counter-productive to try to link everything to climate change. Like crying "Wolf!" instead of galvanizing a populace to action, yelling "Global Warming!" all the time makes people roll their eyes, shake their heads and groan :Again?"

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