Cover Image: July 2012 Scientific American Magazine See Inside

Microbes Manipulate Your Mind [Preview]

Bacteria in your gut may be influencing your thoughts and moods














Share on Tumblr



Image: Brian Stauffer

In Brief

Moody Microorganisms

  • Bacteria and viruses dwelling in our gut produce compounds that can interact with our nervous system in ways that appear to affect our anxiety and stress responses.
  • Early clinical trials suggest that bacterial remedies, such as probiotic supplements, may be useful in treating several types of psychological distress.
  • Eventually individual assessments of gut microbial communities could allow physicians and researchers to tailor treatments for mental disorders.

The thought of parasites preying on your body or brain very likely sends shivers down your spine. Perhaps you imagine insectoid creatures bursting from stomachs or a malevolent force controlling your actions. These visions are not just the night terrors of science-fiction writers—the natural world is replete with such examples.

Take Toxoplasma gondii, the single-celled parasite. When mice are infected by it, they suffer the grave misfortune of becoming attracted to cats. Once a cat inevitably consumes the doomed creature, the parasite can complete its life cycle inside its new host. Or consider Cordyceps, the parasitic fungus that can grow into the brain of an insect. The fungus can force an ant to climb a plant before consuming its brain entirely. After the insect dies, a mushroom sprouts from its head, allowing the fungus to disperse its spores as widely as possible.


Buy This Issue
If your institution has site license access, enter here.
Rights & Permissions

10 Comments

Add Comment
View
  1. 1. IncredibleMouse 09:09 PM 6/20/12

    My gut sent me here.

    Reply | Report Abuse | Link to this
  2. 2. jtdwyer 11:50 AM 6/26/12

    My brain is telling me to reject this nonsense, but my gut tells me there may be something to this...

    Reply | Report Abuse | Link to this
  3. 3. LarryW 12:04 PM 6/26/12

    We're all just dung for some other life-form

    Reply | Report Abuse | Link to this
  4. 4. cdmgsdad 12:18 PM 6/26/12

    More reason to keep our minds out of the sewer.

    Reply | Report Abuse | Link to this
  5. 5. The Mix -UAB 07:51 PM 6/27/12

    This adds to a slew of great microbe theories getting more notice in recent weeks. Others include that humans and their bugs now represent a single super-organism, and that the complex part of our immune system did not evolve to fight invading pathogens. That talent may have been a lucky aftereffect of its more ancient role: managing the bugs our vertebrate ancestors "invited" in to help us better digest more kinds of food.

    Reply | Report Abuse | Link to this
  6. 6. bucketofsquid 11:59 AM 6/29/12

    I've always thought "probiotics" is garbage because different people have different diets and different ancestral adaptations. It does however, make sense that you are literally what you eat and what you eat is based on what your gut bugs need to nourish you. I look forward to more information and possibly the chance to ditch the array of pharmaceuticals I currently depend on. I'd have to see a lot of proof before I'd be willing to risk it though.

    Reply | Report Abuse | Link to this
  7. 7. dchampeau 01:24 PM 7/4/12

    I suggest reading the book Body Ecology Diet for more info on microbes-of-the-gut and how they work with the systems of the human body.

    Reply | Report Abuse | Link to this
  8. 8. Mythusmage 04:49 PM 7/6/12

    What happens when a cat refuses to eat a T. gondii infected rodent?

    How do cats behave around humans?

    How do humans behave around God?

    Ever think that religion is the result of T. gondii infections?

    Reply | Report Abuse | Link to this
  9. 9. tolson in reply to jtdwyer 06:24 PM 7/10/12

    awesome response!!!!!!!!!!!!!

    Reply | Report Abuse | Link to this
  10. 10. AbuZayd in reply to bucketofsquid 12:13 AM 7/16/12

    "I'd have to see a lot of proof before I'd be willing to risk it though."

    Having attended medical school, knowing the studies that are the basis for medications prescribed nowadays, I think you should apply your same logic to those medications, considering the great potential for harm with them. Probiotics are harmless at worst. Actually, we prescribe probiotics quite regularly these days in almost all hospitals to prevent GI infections. If the gut is healthy, often the patient heals as well.

    Reply | Report Abuse | Link to this
Leave this field empty

Add a Comment

You must sign in or register as a ScientificAmerican.com member to submit a comment.
Click one of the buttons below to register using an existing Social Account.

More from Scientific American

Follow Us:

See what we're tweeting about

Scientific American MIND

Tweets could not be retrieved at this time

Free Newsletters


Get the best from Scientific American in your inbox

Solve Innovation Challenges

Powered By: Innocentive

  SA Digital
  SA Digital

Science Jobs of the Week

Email this Article

Microbes Manipulate Your Mind: Scientific American Mind

X
Scientific American MIND iPad

Tap into your MIND

Get Both Print & Tablet Editions for one low price!

Subscribe Now >>

X

Please Log In

Forgot: Password

X

Account Linking

Welcome, . Do you have an existing ScientificAmerican.com account?

Yes, please link my existing account with for quick, secure access.



Forgot Password?

No, I would like to create a new account with my profile information.

Create Account
X

Report Abuse

Are you sure?

X

Institutional Access

It has been identified that the institution you are trying to access this article from has institutional site license access to Scientific American on nature.com. To access this article in its entirety through site license access, click below.

Site license access
X

Error

X

Share this Article

X