New Flu Strain Makes Health Experts Nervous

Is a new strain of H3N2 swine flu a danger to public health or just to the reputations of public health experts?















Share on Tumblr



Image: Flickr/gilt gluttony

A new variant of an influenza virus that circulates in pigs has been jumping occasionally into people, providing a surprisingly early opportunity for public health officials to test out some of the lessons learned from the 2009 H1N1 pandemic.

Since the virus was first spotted in July, there have been 10 cases, all but one of which were children under the age of 10. (The exception was a 58-year-old.) All the cases have been in the U.S.; there have been no reports of this virus in people or pigs anywhere else

The most recent infections, in three young children in Iowa, almost certainly involved person-to-person spread. The Iowa cluster is likely larger—no one in the first child’s family had exposure to pigs, suggesting an unidentified person was the source of virus.

The cases leave public health authorities in the U.S. and elsewhere wondering if a new swine-origin flu virus is circulating at low levels among humans—and what needs to be done if that is indeed happening. (Read “Flu Factories” in the January 2011 Scientific American (preview) to learn why health authorities fear the next pandemic virus may emerge as a result of industrial farming  practices.)

Given the mercurial nature of flu viruses—which can easily mutate into lethal pathogens—ignoring the new virus is not an option, even though to date there have been no deaths and most of the infections have produced only mild symptoms. But the widespread perception that the 2009 swine flu pandemic was much ado about nothing means health authorities risk further damage to their already battered credibility if they sound an alarm and this virus turns out to be a dud. And they know it.

The World Health Organization is working to be ready to react if needed, but wants to make sure it neither underplays or overplays its response to this potential new threat, which is technically known as a swine origin influenza A virus of the H3N2 subtype. The new virus has acquired the M gene of the 2009 pandemic H1N1 virus; studies suggest that this gene may enhance transmissibility of the virus.

"We are closely following the information coming out of the U.S. And we just are making sure that if we need to be more active, we will be more active, or if we need to stand down we can do so,” says Keiji Fukuda, the UN health agency’s assistant director-general for health security and environment.

Among the things the WHO is working on is finding a scientifically correct yet politically sensitive name to call this virus. Sales of pork plunged in 2009 when the new H1N1 was identified as swine flu, a reference to the fact it was comprised mainly of genes from flu viruses that circulate in pigs.

This H3N2 poses similar naming challenges. There is already a human H3N2 — a distant cousin of this pig virus — so some way to differentiate the viruses is needed. Pork producers are concerned about how communications about the virus will be handled, admits Paul Sundberg, vice-president for science and technology for the National Pork Board, who says his group has already met with officials at the Centers for Disease Prevention and Control in Atlanta to discuss the naming challenge.

Fukuda says the WHO is trying to draw on the experience of 2009 as it maps out its response to the new virus. “It frequently comes up as a question: ‘What did we learn from that pandemic that we ought to be thinking about in terms of this situation?’”



12 Comments

Add Comment
View
  1. 1. oldvic 07:59 AM 12/2/11

    At the beginning of the article, the pig looking at the camera is thinking "Be ready for our revenge..."

    Reply | Report Abuse | Link to this
  2. 2. alan6302 12:56 PM 12/2/11

    The "big one" is supposed to be related to ruminants and salmonella.

    Reply | Report Abuse | Link to this
  3. 3. ThanAngell 04:20 PM 12/2/11

    This is the virus to watch out for, for now:
    http://www.npr.org/blogs/health/2011/11/17/142453447/bird-flu-research-rattles-bioterrorism-field

    Reply | Report Abuse | Link to this
  4. 4. DC_Agar 08:33 PM 12/2/11

    I agree that H5N1 is way more frightening, though you never know. For naming purposes, they could call it H3N2 2010 or H3N2-Iowa. Iowa wouldn't suffer much from that, since the public now understands (after 2009) that Iowa is merely the point of first detection. Or how about "Kong Jr"? Naming it for the H3N2 subtype will not confuse the public because most do not know that it has been the most prevalent for more than 40 yrs.

    Reply | Report Abuse | Link to this
  5. 5. DC_Agar in reply to DC_Agar 08:38 PM 12/2/11

    I meant to say, H3N2-2011, not H3N2-2010 (duh)

    Reply | Report Abuse | Link to this
  6. 6. Christine Gorman in reply to ThanAngell 09:14 AM 12/3/11

    Thanks for the link, ThanAngell. I hadn't heard about the Malta episode.

    Reply | Report Abuse | Link to this
  7. 7. willemjanboelemapharma 11:43 AM 12/4/11

    Aren't we creating this all by our own behaviour? I believe this will continue the coming years, with new viruses every other day because of the way we have set-up our supply chain of food. How can we stop this and ensure it does not effect us as much as it does today?

    Organic small farm farming???

    Willem Jan Boelema Pharma

    Reply | Report Abuse | Link to this
  8. 8. Ed Rybicki 05:04 AM 12/7/11

    @willem etc: "Organic small farm farming" is possibly what got a number of epidemics and recombinants / reassortants started, if you believe folk working in flu virus epidemiology - because in southern China, the close proximity of humans, pigs, ducks, horses ands their waste on small farms provided an ideal mixing ground for the emergence of novel flu viruses.

    So yes, we are creating the whole phenomenon because of our behavior - but organic farming is NOT the way to solve it.

    Reply | Report Abuse | Link to this
  9. 9. bucketofsquid in reply to willemjanboelemapharma 10:39 AM 12/7/11

    Organic small farming also tends to not produce as much food so we would have to choose to let people starve. No thanks.

    Reply | Report Abuse | Link to this
  10. 10. ErnestPayne 05:08 PM 12/8/11

    You can never really take enough precautions when it comes to contagion. No matter how much the great unwashed ridicule the situation.

    Reply | Report Abuse | Link to this
  11. 11. ncubeeight 05:24 PM 12/8/11

    We could call it "The other white meat flu" for political correctness.

    Reply | Report Abuse | Link to this
  12. 12. MrJames 07:43 AM 1/12/12

    To become knowledgeable about flus may I suggest Dr. Nathan Wolfe's "The Viral Storm: The Dawn of a New Pandemic Age." National Public Radio has an interview with him online and the book has solid information throughout. Viral hunting and staying ahead of mass infections is both more interesting and and more scary than many imagine. Dr. Wolfe is one of the most qualified, check out his credentials, to write such a book. Hope this helps. This information should be common knowledge to every high schooler.

    Reply | Report Abuse | Link to this
Leave this field empty

Add a Comment

You must sign in or register as a ScientificAmerican.com member to submit a comment.
Click one of the buttons below to register using an existing Social Account.

More from Scientific American

See what we're tweeting about

Scientific American Editors

More »

Free Newsletters


Get the best from Scientific American in your inbox

Solve Innovation Challenges

Powered By: Innocentive

  SA Digital

Latest from SA Blog Network

  SA Digital

Email this Article

New Flu Strain Makes Health Experts Nervous

X
Scientific American Magazine

Subscribe Today

Save 66% off the cover price and get a free gift!

Learn More >>

X

Please Log In

Forgot: Password

X

Account Linking

Welcome, . Do you have an existing ScientificAmerican.com account?

Yes, please link my existing account with for quick, secure access.



Forgot Password?

No, I would like to create a new account with my profile information.

Create Account
X

Report Abuse

Are you sure?

X

Institutional Access

It has been identified that the institution you are trying to access this article from has institutional site license access to Scientific American on nature.com. To access this article in its entirety through site license access, click below.

Site license access
X

Error

X

Share this Article

X