- Pill cameras made possible unprecedented internal views of the entire digestive tract, but the uses and accuracy of those passive capsules are limited.
- Active pill-size robotic capsules are being developed for use in screening, diagnosis and therapeutic procedures.
- Miniaturizing robotic components to perform tasks inside the body poses novel engineering challenges. Those challenges are giving rise to creative solutions that will influence robotics and other medical technologies in general.
The movie Fantastic Voyage, the story of a miniaturized team of doctors traveling through blood vessels to make lifesaving repairs in a patient’s brain, was pure science fiction when it came out in 1966. By the time Hollywood remade the film in 1987 as Innerspace, a comedy, real-world engineers had already begun building prototypes of pill-size robots that could voyage through a patient’s gastrointestinal tract on a doctor’s behalf. Patients began swallowing the first commercially built pill cameras in 2000, and since then doctors have used the capsules to get unprecedented views of places, such as the inner folds of the small intestine, that are otherwise difficult to reach without surgery.
One important aspect of Fantastic Voyage that has remained fantasy is the notion that such tiny pill cameras could maneuver under their own power, swimming toward a tumor to get a biopsy, checking out inflammation in the small intestine, or even administering drug treatments to an ulcer. In recent years, however, researchers have made great strides in converting the basic elements of a passive camera pill into an active miniature robot. Advanced prototypes, now being tested in animals, have legs, propellers, sophisticated imaging lenses and wireless guidance systems. Soon these tiny robots may be ready for clinical trials. Right now they are testing the limits of miniaturized robotics.
This article was originally published with the title Robot Pills.