Cover Image: August 2002 Scientific American Magazine See Inside

Soft Manufacturing [Preview]

Shaping small structures in rubber has moved beyond a Harvard lab















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PEELING OFF a rubber sheet allows Surface Logix scientists to test how cells placed in micromolded cavities react to a drug candidate

PEELING OFF a rubber sheet allows Surface Logix scientists to test how cells placed in micromolded cavities react to a drug candidate (cells not shown). Image: EMANUELE OSTUNI Surface Logix

George M. Whitesides is a towering figure in the emerging field of nanotechnology. This Harvard University chemistry professor has articulated the promise of a new discipline for building things with dimensions as small as a few atoms. Whitesides has not been content, however, to keep his work confined to an academic laboratory that today boasts about 40 graduate and postdoctoral students.

He has established a company that fabricates microsize and nano-size components in soft materials to help the pharmaceutical industry perform tests on biological samples. The technology invented by Whitesides and his collaborators, known as soft lithography, is one of a number of radically new manufacturing techniques that can make large numbers of small structures [see "Breaking the Mold," Innovations, July].


This article was originally published with the title Soft Manufacturing.



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