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The autoimmune reaction responsible for type I diabetes arises when the immune system mistakes proteins that are made by pancreatic beta cells (the insulin producers) for foreign invaders. The resulting attack, targeted to the offending proteins, or "autoantigens," destroys the beta cells (above). Eating small amounts of autoantigens quites the process in diabetic mice, for unclear reasons. The autoantigens might act in part by switching on "suppressor" cells of the immune system (inset), which then block the destructive activities of their cousins (below).
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