Science has become the ultimate source of the most influential ideas transforming the world. Consider the evidence. Computers are the engines of the global economy. Three of the biggest international controversies are over the use of genetically modified crops, the prevention of global warming, and the feasibility of antimissile defenses. Some people even look to physics and cosmology for clues to the nature of God.

For readers of Scientific American, this is not news. This magazine has always been a must-read for the inexhaustibly curious, the ones who passionately want to understand what makes the world tick and who recognize that--especially in a technology-driven society--the only way to that enlightenment is through scientific discovery. For 155 years SA has been where they could turn for answers.

This article was originally published with the title The 21st-Century Handbook.

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