The Brain May Use Only 20 Percent of Its Memory-Forming Neurons

Study shows that that pace at which a brain cell activates a key protein may influence its role in memory formation—a finding that could lead to new Alzheimer therapies















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In the future, Josselyn says, this mechanism could be harnessed to produce a new treatment for Alzheimer's disease. "In time, we're going to have some sort of neuron-replacement therapy for Alzheimer's," she says, conceding, "It's a little sci-fi right now." But, if new neurons are inserted into a damaged brain, modulating CREB function could help bias the healing brain to use the functioning neurons and not its injured population.



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  1. 1. mike5 11:51 PM 3/13/13

    Don't sacrifice the science to make a headline with a hook. You write yourself that "it is the same percentage [ie 20%], but not the same neurons..." So clearly, the brain uses more than 20% of its neurons, giving the lie to your title. Another assumption you're cheerfully allowing people to make is that this is in human brains, which of course were not studied.

    Also, did the scientists study the % of neurons activated in CREB-normal mice? 20% might be the minimum necessary--which would be an interesting finding--but perhaps say, 30% is the normal level in normal animals? If this was studied, that should have been mentioned.

    A non-misleading version of your current title would be "A mouse brain can get by with 20 percent of its memory-forming neurons", which is not very snappy. The title needs a totally different direction.

    As a scientist myself I know you're fed a lot of hyperbole from abstracts, press releases, impact statements, quotes, the list goes on... Don't make it worse by adding your own.

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