The Proof Is in the Proteins: Test Supports Universal Common Ancestor for All Life

One researcher put the basic biological assumption of a single common ancestor to the test--and found that advanced genetic analysis and sophisticated statistics back up Darwin's age-old proposition















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Murky origins
Theobald says his most surprising results were "how strongly they support common ancestry." Rather than being disappointed about simply backing up a long-held assumption, he says that at least, "it's always nice to know that we're on the right track."

These findings do not mean that a universal common ancestor establishes the "tree of life" pattern for early evolutionary dynamics. Nor, however, do they infer a "web of life" structure. The tree versus web debate remains "very controversial right now in evolutionary biology," Theobald says, reluctant to pick a side himself.

One of the other big unknowns remaining is just when this universal common ancestor lived and what it might have looked like—a question that will take more than Theobald's statistical models to answer. Theobald also notes that the support for a universal common ancestor does not rule out the idea that life emerged independently more than once. If other, fully distinct lineages did emerge, however, they either went extinct or remain as yet undiscovered.

Research will likely push on into these dusky corners of early evolution, Penny notes, as "scientists are never satisfied." He expects that researchers will try to sort back even earlier, before DNA took over, and assess the early stages of evolution during the RNA days.

On a more foundational level, Penny says, the paper should not put an end to the assessment of ancestral assumptions. Instead it should be a reminder that "we have never thought of all possible hypotheses," he says. "So we should never stop considering some new approach we haven't thought of yet."

*Erratum (5/13/10): This sentence was changed after publication. It originally stated that a universal common ancestor is more than 10 times more likely. 



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  1. 1. Jsbrasino 02:50 PM 5/13/10

    So life just evolved once.... Or we ate all the other parallel forms. Seems unlikely. Maybe evolving life is a very very very rare event and we are here do to panspermia?

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  2. 2. chubbee 04:45 PM 5/13/10

    Or perhaps that "common ancestor" is the first logical life form to emerge given the elements making up the environment of this world.
    So no matter how many times life forms, it begins there.

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  3. 3. Norway Man 04:49 PM 5/13/10

    Think about it.

    We might be totally alone in the universe! Or at least so enormously far from an other intelligent life form that it is impossible for us to ever detect them.

    I think we are her because it is so exactly right conditions on earth, in the solar system and in this region of space. Then we had so enormously much luck when life started and now is the exact time when "we" the intelligent life form has started to look in to space and ask the grand question: Are we alone?

    Answer: Yes, it is highly possible.

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  4. 4. agenthucky in reply to chubbee 05:27 PM 5/13/10

    But the big question is how the subsequent life forms began. Where they made up of a different sequence of elements in our environmental world, or did it get rooted in the one that already formed?

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  5. 5. agenthucky in reply to Norway Man 05:32 PM 5/13/10

    Luck may have something to do with it, but luck isn't scientific (even if it is realistic). Statistically speaking, even though we are considered "lucky", the probabliity we are alone is small.

    You can account for all the "luck" you want, but when you define that luck, we can see that there are many (out of an infinite source) cases where it is the same.

    Bottom line, even if we were extremely lucky, statistics say that the scenario is repeatable.

    The odds might be so against us finding it, that we might not ever, but to say it is probable that it isn't there, is a huge leap.

    Possible, yes, probable, no.

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  6. 6. agenthucky in reply to Norway Man 05:40 PM 5/13/10

    Also an interesting point is the possibility of life on Europa. There won't be any "intelligent" life there, but if we see life, it could be the common ancestor of the life on that planet. We cannot say for sure evolution happens on other planets, or at a rate that makes it noticeable, but if we were to find simple life-forms, this study can help show the possibility of intelligent life forming.

    An even more intersting point, if we did find simple life-forms, we could witness the early stages of life, where as we were not around to witness and document ours. That is where this study can become extremely important to more than just our past. Not to say that we'll be around billions of years to witness the whole thing!

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  7. 7. John_Toradze in reply to agenthucky 06:43 PM 5/13/10

    If we go to europa, we will seed it with bacterial/archael/fungal life from earth.

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  8. 8. mihondo2010 08:31 PM 5/13/10

    It is really hard to assign a probability of the appearance of 'life' when 1) you have a known statistical population of 1 (earth), and 2) you don't have a known mechanism for the initiation of life (Genesis doesn't count). You can throw all sorts of multi-magnitude assumptions together and make wild guesses, but in the end... we just don't know how easy/hard/often life starts.

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  9. 9. vendicar9 02:00 AM 5/14/10

    "So life just evolved once.... Or we ate all the other parallel forms. Seems unlikely. Maybe evolving life is a very very very rare event and we are here do to panspermia?" - Blah

    A large forest fire is lit only once. Once burned it prohibits ignition from other sources. The probability of ignition at any point is vanishingly small.

    I fail to see the problem.

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  10. 10. vendicar9 02:02 AM 5/14/10

    "Also an interesting point is the possibility of life on Europa" - yawn

    Cold. Low energy. Slow chemistry.

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  11. 11. antonl in reply to Jsbrasino 04:51 AM 5/14/10

    It does make panspermia seem a bit unlikely, doesn't it?

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  12. 12. Telrunya 10:35 AM 5/14/10

    Well here is the crux. What are his evolution models based on and what variables do they take into account? If his models follow the same exacting style of criteria that climate models do then we can safely throw this report on the same junkscience pile with most of the rest of what SciAm prints

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  13. 13. buddhacosmos 12:39 PM 5/14/10

    I am always thinking that convergent evolotion implies there is a determinism in how life proceeds and what it caan produce as features. i can kind of extend this to the first life. that when life appeared there is only one possible combination of elements and characteristics. that there maybe only one possible primordial cell.

    with the astounding advent of life , i think it has a fundamental universal form of origin.

    of course if we could find alien life on Mars and Europa it might tell us if there is one possible progenitor of life.

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  14. 14. SpoonmanWoS in reply to vendicar9 02:34 PM 5/14/10

    @vendicar9: it's cold, but there are also hot spots where extromophiles might be found. The gravitational forces on Europa cause significant crust migration and friction which leads to areas highly conducive to life. We're most likely not going to find life all over Europa*, but it appears all of the basic building blocks are there, there's spots where it's warm enough...

    *Although, we could. Life on Earth has diversified enough that there are extremophiles that live in extremely cold areas on the planet. Why couldn't life emerge in the hot spots and then migrate to the colder areas?

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  15. 15. Ehkzu 01:13 AM 5/15/10

    The book "Rare Earth" makes an educated, albeit speculative, argument for life in the universe being fairly common in solar systems with stable enough stars (G or K class--hotter stars get hotter too quickly; cooler ones "burp" periodically, nuking nearby planets) in single star systems with a rocky planet that has a magnetosphere, located in the solar system's life zone (i.e. where water is liquid).

    That's for bacterial life, however. For more advanced life you need to throw in a big Moon like ours, the "Rare Earth" authors claim. It's needed to give the planet axial stability, without which the long-term weather systems would be too extreme for advanced life. And throw in a Jupiter-class gas giant farther out to "vacuum" up asteroids and comets, keeping the asteroid strike count down to a dull roar, of course.

    Still, with hundreds of billions of stars in hundreds of billions of galaxies in our universe alone (and there may be who knows how many other anthropogenic universes), the simple odds of Earth's unusual set of circumstances repeating millions and millions of times is, well, astronomical.

    The problem is how far. And there, unfortunately, is the kicker. Even if every single other solar system in the universe had intelligent life, sublight travel (the only kind there is in all likelihood) would make it a minimum 60,000 year or so round trip even to/from Alpha Centauri.

    So the very best we can hope for is radio contact--and even there, say the nearest technical civilization is, oh, 40 light years from here. So I say "Hi; they reply promptly, but I've died before hearing back. Some conversation.

    So whether we're unique or not we're probably stuck with ourselves. To think that means we're the only ones out there though...well, that's the actual leap. Not the other way around.

    www dot blogzu dot blogspot dot com

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  16. 16. TMK in reply to antonl 11:12 AM 5/15/10

    @ antonl - I'm not sure if this entirely rules out panspermia... maybe not that 'life' was seeded from other planets, but what about the building blocks of life.

    I think it was pretty recent that researchers found amino acids on a comet... Check out this link for a cool video on this stuff. http://www.scienceinseconds.com/video.php?vId=117&tId=

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  17. 17. Extremophile 03:56 PM 5/17/10

    May I clarify the discussion somewhat?

    The article as well as Darwin's books discuss the origin of species, not the origin of life.

    We know a lot about evolution and the development of new species from older forms.

    But we know nothing about the origin of life at all. Except, maybe, that it seems very unlikely that life could start at all.

    But it has somehow happened.

    But friends, this is a completely different story.

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  18. 18. dling 10:47 PM 5/17/10

    Your assertion that "we" (and unfairly including the entire discipline of science along with our own ignorance) know nothing about life's origin is utterly incorrect. For example, we know quite precisly the abiotic paleoenvironmental conditions. We know the time. What we don't know undoubtedly is greater than what we do know, but the exciting thing is not the retelling of a all-too-familiar old myth. What is exciting to the scientist is the question of what happened in between those early abiotic, anaerobic, radiated, NEO bombarded conditions, and the RNA-dominated code of life that emerged shortly after. The exciting question is precisely how was the code for life replicated before RNA? There are many possible answers, all of which are fascinating studies, and all of which may have played a part.

    One problem is that we cannot run the experiment over again. However, in case you refuse to ponder one profound logical extension - that doesn't mean it never happened.

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  19. 19. Wayne Williamson 09:02 PM 5/18/10

    nice article...i hope someone(s) follow up and either proves it or disproves it or qualifies it....sounds like its a first step....

    Reply | Report Abuse | Link to this
  20. 20. bigbaddude 08:12 AM 5/20/10

    Evolution is for those who refuse to eccept the obvious.
    God created us we are his children.
    Do not be fraid of the truth. Talk to Jesus!

    Reply | Report Abuse | Link to this
  21. 21. Wayne Williamson 03:34 PM 5/23/10

    bigbaddude...probably should change your name to smallscaredchild.....

    Reply | Report Abuse | Link to this
  22. 22. ajhil in reply to Telrunya 03:09 PM 8/30/10

    "Junk science" is a term employed by industry-sponsored climate change deniers and the dupes who echo them, not by reputable scientists.
    Current theories of global climate change are supported by a wide range of empirical data and not solely by the results of computer modeling.
    Nevertheless, models have been very successful in reproducing observed changes in global climate.
    My guess: you aren't in the least qualified to critique the models or the science of global warming. You're just blowing smoke based on right wing political ideology.
    Give it a rest. You're only singing to the ultraconservative choir.

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