C. IMMITIS: The microscopic spores of Coccidioides immitis hide in dust and are inhaled, causing valley fever in the desert U.S. Southwest.
Image: Courtesy of Wikipedia
Dry dust baked in this summer's heat wave might be driving up valley fever cases across the southwestern United States.
California and Arizona have reported increases in this fungal infection this year, part of a rising tide spanning the past decade. "Recent increases in rates have been reported," said Matt Conens at the California Department of Public Health in an email. "The reasons are unclear but may include changes in reporting, cyclical changes and increased migration into endemic areas." Some experts, however, think the changing climate may also be an ingredient.
The illness is caused by Coccidioides immitis and Coccidioides posadasii, fungi that dwell in certain types of soil found mainly in desert regions spanning northern Mexico, Texas, Arizona, New Mexico and Southern California.
Antje Lauer, a microbiologist at California State University, Bakersfield, explained that in most environments, bacteria and other organisms keep the pathogen in check. But when the temperature rises and rainfall slows to a trickle, these hurdles fall and the fungi can surge. Lauer said in these conditions, Coccidioides forms spores to survive and give it a head start once the rain starts to fall again.
These spores can break off in the desert wind, lofted to areas where people can breathe them in and causing coccidioidomycosis, also known as valley fever. "Only a few spores are needed to cause the disease," Lauer said.
Roughly 60 percent of infected people do not experience any problems, but the remainder can suffer flu-like symptoms along with rashes and muscle pain. In a small fraction of cases, the fungus can spread beyond the lungs into other tissues, which can be deadly.
In the United States, about 150,000 fall ill from coccidioidomycosis annually. Between January and July this year, 8,969 valley fever cases were reported to the state, almost double the five-year median of 4,507, according to the Arizona Department of Health Services. Conens said data on this year's illnesses in California won't be available until next year.
Difficult to monitor, easy to misdiagnose
However, researchers said these numbers might not reflect reality, since the disease is frustratingly mercurial, as it is difficult to monitor, diagnose and treat.
"We're only capturing the tip of the iceberg," said Clarisse Tsang, acting manager of the Infectious Disease Epidemiology Program at the Arizona Department of Health Services. She observed that many people who do get sick don't end up going to the doctor, so those cases are not reported. Of patients who do get medical attention, many physicians misdiagnose the illness. Doctors who get it right do not always let state health officials know.
The disease also takes from one to four weeks to develop, so there is a substantial lag between when people are exposed and when state health officials start finding out.
As a result, health officials only have a loose grasp on how valley fever is changing and spreading. This has tremendous consequences for employers, since infected individuals miss a median of 14 days of work, according to Tsang. "The economic impact of valley fever is probably grossly underestimated," said Joe Tabor, an assistant professor at the College of Public Health at the University of Arizona.
Figuring how valley fever interacts with the environment has also been a struggle. Unlike viruses or bacteria, Coccidioides cannot spread between people and is not transmitted through vectors like mice and mosquitoes; it is simply from the environment. "Most of the understanding of the ecology of valley fever occurred in the '60s, and not a lot of progress has been made," Tabor said.
Hard to capture
Part of the reason is data are hard to come by. Coccidioides spores are difficult to find in the soil, growing in patches spread out over wide areas. "You can move over just a few feet and you can't find it," Tabor said. Tracking the disease in the air is even more troublesome, he added, noting that no one has yet isolated spores from air samples, although one attempt to do so led to a scientist coming down with valley fever.
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5 Comments
Add CommentAnimals are affected too.
Reply | Report Abuse | Link to thisWithout a national health care system the disease could be far more dangerous and under recorded.
Reply | Report Abuse | Link to thisLOL--Climatewire promotes ever more mindless propaganda.
Reply | Report Abuse | Link to thisEvery summer Phoenix has haboobs--gigantic dust storms thousands of feet high and dozens of miles wide that roll out of the desert from the south. I have lived in the area since 1990 and cannot remember ever experiencing more than 5 per year. But not this year! So far in 2012, there have 30 or more (not sure of exact number, since I stopped counting at 22); in one 24-hour period, there were two of them. Last year the count was up, but nothing like this year. The Health Department was expecting an increase in Valley Fever cases; their expectations have been realized, and the haboob season is still ongoing.
Reply | Report Abuse | Link to thisALL persons living in the desert southwest are presumed to be exposed, yet 60% of those, as evidenced by antibody titers, never become ill or experience only a mild respiratory-type sickness. It is transmitted by inhalation of spore-containing dust; it is not transmissable person-to-person.
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