Shortly after moving to Canada’s Okanagan Valley, Patricia Lee started experiencing severe irregularities in her menstrual cycle. She had one period that lasted two and a half months. The bleeding was so intense that at one point, doctors recommended a blood transfusion.
“I couldn’t sleep – it was excruciatingly painful and I grew quite weak,” said Lee, now 47. Her diagnosis: a fibroid, or benign tumor, the size of a ping-pong ball in her uterus, and two cysts in her ovaries.
At the time, Lee lived in a long, slender valley through the center of British Columbia that produces nearly all of the province’s tree fruits and grapes. Agriculture is intensive there, as is pesticide use.
Lee will never know what role, if any, her environment played in causing her uterine fibroids. But scientists have long suspected a link between hormone-disrupting chemicals in the environment and gynecological diseases.
Research investigating these links has had mixed results. Now, several new studies are adding to the evidence that estrogen-mimicking pesticides and industrial chemicals may increase women’s risk of uterine and ovarian diseases – helping to solidify a theory that emerged two decades ago.
“Our studies are beginning to corroborate the idea that environmental estrogen may be associated with endometriosis,” said Germaine Buck-Louis, director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development’s epidemiology division in Maryland.
Back in 1993, a connection between endometriosis and environmental chemicals was discovered. Rhesus monkeys fed food contaminated with dioxins – hormone-disrupting pollutants created by waste incinerators and other industries – developed endometriosis 10 years later.
Endometriosis, when uterine tissue grows in the ovaries or other parts of the body, often causes pelvic pain and infertility. An estimated 10 to 20 percent of reproductive-age women in the United States suffer from it, according to the Endometriosis Foundation of America.
In a major new study, two groups of women in the Salt Lake City and San Francisco areas – one group with pelvic pain and the other with no symptoms -- were more likely to be diagnosed with endometriosis if they had high blood levels of the estrogen-like pesticide hexachlorocyclohexane (HCH) than women with low levels. HCH has been banned as a crop pesticide in the United States but it builds up and persists in the environment, so it remains in some food supplies.
Calling the study “revolutionary,” Buck-Louis said that finding the link between the pesticide and endometriosis in both groups “is a pretty strong signal” that the connection is real.
Also, women in the same group with the highest levels of a sunscreen chemical, benzophenone, in their urine had a 19 percent higher risk of endometriosis than women with the lowest levels, according to research published in Environmental Science and Technology.
And in Italy, women had endometriosis more often if they had higher levels of two banned chlorinated chemicals that can disrupt hormones – polychlorinated biphenyls (PCBs) or residue of the insecticide DDT, according to a 2009 study of 158 women.
Recent research has uncovered links to other gynecological problems, too. Women in Greece diagnosed with polycystic ovary syndrome (PCOS) – which causes irregular menstrual periods, infertility, weight gain and excessive hair growth – were more likely to have higher blood levels of the estrogen-mimicking chemical bisphenol A than women without the disease, according to a study published last year.
“It’s certainly plausible that any outside source that alters estrogen levels, even slightly, could contribute to gynecological diseases,” said Dr. Megan Schwarzman, a family physician at San Francisco General Hospital and an environmental health scientist at the University of California, Berkeley.
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Add CommentIn men, the outcome of Prostate cancer is influenced by the amount of milk and dairy products they consume, because industrial milk has a higher progesterone content, cattle is kept in a fake continued pregnancy hormonal condition to increase the milk output of the animal, it can be discussed if the amount of milk and dairy products consumed may have also some influence in women's health.
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Endometriosis may have a link also to changes in the tumor suppressor gene p53, so it's not surprising that women suffering this ailment have also an increased cancer risk. Usually, experts say that cancers in developing countries are linked to genes, with the notable divergences from this rule of cancers linked to EBV, Hepatitis Virus, and food contaminants as Aflatoxins, while cancer in industrial world would be linked to environmental carcinogenesis. It must be also remarked that the longer you live, the higher your chances of having a cancer are, and in female tumors, social-induced health changes such as a delay in the age of first pregnancy, no pregnancies at all and less breastfeeding time is linked to more breast cancers, and a higher number of ovulating cycles may increase the incidence of ovarian cancer, this would be the reason for the protective effect on this "silent killer" of using oral combined hormonal drugs ("the pill"), this may be a reason good enough for taking these drugs, as long as an adequate history rules out coagulation and other disorders than can worsen with the use of hormones. There are other hormone linked or hormone like influences in gynecological and other cancers, but tobacco use of any kind and high alcohol intake continues being the most dangerous causative effect in many cancers.
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