ADVERTISEMENT

Transfer Troubles

Cloning success in animals doesn't extend to humans
DISH-DEFYING



MAURO FERMARIELLO/SCIENCE PHOTO LIBRARY

Mice and pigs are easy; rats are harder. Humans are harder still, but not as hard as monkeys. No one knows why some species are tougher to clone than others. But studies with mice are helping define those differences and should ultimately enable researchers to achieve greater success in obtaining human embryonic stem cells to treat diseases and replace organs.

In terms of therapeutic cloning (otherwise known as nuclear transfer), the most notable achievement so far comes from Woo Suk Hwang of Seoul National University. In February his lab reported on how it transferred the nuclei of several human donor cells into 242 eggs that had their nuclei removed. The batch produced 30 blastocysts (an early stage of embryonic development), of which only one yielded a self-renewing stem cell line.

This article is only available as a PDF.

Select an option below:

Customer Sign In

*You must have purchased this issue or have a qualifying subscription to access this content

Rights & Permissions
Share this Article:

Comments

You must sign in or register as a ScientificAmerican.com member to submit a comment.
Scientific American Special Universe

Get the latest Special Collector's edition

Secrets of the Universe: Past, Present, Future

Order Now >

X

Email this Article

X