See Inside Scientific American Mind Volume 24, Issue 2

Why Doctors Prescribe Off-Label Drugs

Why your doctor might give you an antidepressant to treat your migraines

Every prescription drug available in the U.S. has been approved by the Food and Drug Administration via a lengthy, expensive process of clinical trials. These trials show that the drug is safe and effective at treating a particular condition. But doctors often prescribe drugs off-label, for conditions they are not approved to treat. Here's why.

This article was originally published with the title "The Unadvertised Uses of Drugs."

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