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A cure for the common cold? Culprit genome sequenced, but ...

Could the common cold become a thing of the past? Scientists have unraveled the genetic code for all 99 strains of the rhinovirus, but there may be a disconnect between excitement over the feat in the lab versus at pharmaceutical companies that would ordinarily develop a cure or vaccine against infection.

The discovery, published this week in Science, means that, in theory, drug or vaccine developers have a map of possible targets against the cold virus. "There is real promise now, based on full understanding of this virus, that we have never had before," study co-author Stephen Liggett, a professor of medicine at the University of Maryland School of Medicine, told the Baltimore Sun. "Let's get, perhaps, a single pill [that] will kill the virus that day, that moment, and within six hours you are cured. It is possible."

Can a good night's sleep prevent a cold?



People who get less than seven hours of shut-eye nightly are three times more likely to catch a cold than those who get eight or more hours, according to a new study. Researchers speculate that a lack of sleep may compromise immune function, making people more vulnerable to the common cold. 

"The really striking thing about this study for us is how little differences in sleep can have a big impact on your susceptibility," says Sheldon Cohen, a psychoneuroimmunologist at Carnegie Mellon University in Pittsburgh, Pa., and lead author of the study published today in the Archives of Internal Medicine

Previous research has shown that sleep deprivation may trigger changes in the immune system that could make a person more vulnerable to infection. For example, poor sleep may lead to a dip in the number of killer T-cells, which destroy viruses and bacteria, as well as to lower levels of interleukin-2, a protein that stimulates production and growth of many infection-fighting cells, including T-cells. But this is one of the first studies that links sleep deficits to increased susceptibility to the rhinovirus, the most common culprit behind, well, the common cold.


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