News Blog

News Blog


An eyetooth for an eye: A rare transplant restores sight to blinded woman

tooth transplant for cornea cure blindnessA 60-year-old Mississippi woman who had been blind for nine years can now see again after doctors implanted one of her teeth into her eye—the first time the surgery had been performed in the U.S. Two weeks after several sessions of intensive surgery, she now has 20/70 vision in one of her eyes, which is predicted to continue improving as it heals.

In 2000, Sharon Thornton was diagnosed with Stevens-Johnson syndrome, a rare disease that can destroy skin—and corneal—cells. Even after she recovered from the disease, brought on by a reaction to her medication, her corneas—the surface of the eye—were too scarred to allow her to see, or obtain a transplant.

After stem cell treatment in 2003 failed to restore her vision, doctors went looking for alternatives. Victor Perez, an associate professor of ophthalmology at the University of Miami Bascom Palmer Eye Institute, decided to attempt modified osteo-odonto keratoprosthesis (MOOKP), what he called a procedure "of last resort," in a prepared statement

Teen's broken heart mends--literally--after grafted heart is removed

heart, transplantFourteen years after a risky operation to save the life of an infant suffering heart failure, a team of U.K. doctors is claiming success. Hannah Clark (now aged 16)—who as a baby had a donor heart grafted onto her own—has made a full recovery, three years after the transplanted organ was removed, the doctors claim in an article published online today by The Lancet.

The "full recovery" part comes from the fact that Clark no longer needs to take immunosuppression medication that caused her to suffer from a type of cancer called Epstein-Barr-virus-associated post-transplant lymphoproliferative disorder (EBV PTLD), report the authors, who include Victor Tsang, a pediatric cardiac surgery specialist, and Magdi Yacoub, a professor of cardiothoracic surgery at Imperial College London (both led the surgery in February 2006).

Man gets first double hand transplant in U.S.

double,hand,transplant,kepnerA 57-year-old man from Alberta, Georgia has become the first person in the U.S. to receive a double hand transplant. After undergoing a ten-hour surgery that ended Monday night, the patient, Jeff Kepner, is in critical but stable condition, according to Amy Dugas Rose, a spokesperson for the University of Pittsburgh Medical Center (UMPC), where team of ten surgeons carried out the operation.

Kepner, who lost both hands and feet to a bacterial infection a decade ago, will need intense physical therapy before he is able to use his hands effectively, according to Rose.

Kepner is reportedly receiving a bone marrow transplant from the donor sometime in the next few days, which is part of a special protocol developed at UMPC that aims to minimize the amount of anti-rejection drugs transplant recipients need to take. These drugs, which suppress the immune system, help prevent the body from attacking the transplanted tissue, but they also increase susceptibility to infections and cancer and may eventually lead to kidney failure, says Kadiyala Ravindra, a transplant surgeon at the University of Louisville in Kentucky who has been involved in single hand transplants at Louisville's Jewish Hospital. The idea behind the bone marrow graft, which is not standard in these types of surgeries, is to reeducate the immune system to recognize the transplanted tissue as its own, he explains.

Heart cells found to regenerate

Even though heart attacks may not be deadly, they can leave your ticker damaged. The reason: they occur when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn't restored quickly, a section of the heart muscle becomes damaged from the lack of oxygen and begins to die, weakening its ability to pump blood.

Researchers have long wondered whether such damage could be reversed, that is, whether hobbled heart muscle cells could regenerate — potentially affecting the ability of scientists to hatch ways to repopulate damaged heart tissue. A study in Science today confirms that some heart muscle cells do, in fact, regenerate slowly over the course of a person's lifetime. Scientists from the Karolinska Institute in Sweden report that in early adulthood, we're continually renewing about 1 percent of our heart cells a year; that regeneration slows down, but it still occurs in old age, with a little less than half of 1 percent of cells regenerating at age 75. All told, we've renewed about 40 percent of our heart cells by age 70, neuroscientist Jonas Frisén told Science in a podcast.


Show More Articles

More from Scientific American

See what we're tweeting about

Scientific American Editors

Tweets could not be retrieved at this time

Free Newsletters


Get the best from Scientific American in your inbox

Solve Innovation Challenges

Powered By: Innocentive

  SA Digital
  SA Digital

Email this Article

X
Scientific American MIND iPad

Tap into your MIND

Get Both Print & Tablet Editions for one low price!

Subscribe Now >>

X

Please Log In

Forgot: Password

X

Account Linking

Welcome, . Do you have an existing ScientificAmerican.com account?

Yes, please link my existing account with for quick, secure access.



Forgot Password?

No, I would like to create a new account with my profile information.

Create Account
X

Report Abuse

Are you sure?

X

Institutional Access

It has been identified that the institution you are trying to access this article from has institutional site license access to Scientific American on nature.com. To access this article in its entirety through site license access, click below.

Site license access
X

Error

X

Share this Article

X

About the Bering in Mind Blog

In this column presented by Scientific American Mind magazine, research psychologist Jesse Bering of Queen's University Belfast ponders some of the more obscure aspects of everyday human behavior. Ever wonder why yawning is contagious, why we point with our index fingers instead of our thumbs or whether being breastfed as an infant influences your sexual preferences as an adult? Get a closer look at the latest data as "Bering in Mind" tackles these and other quirky questions about human nature. Sign up for the RSS feed or friend Dr. Bering on Facebook and never miss an installment again.

X

About the Cross-check Blog

Every week, John Horgan takes a puckish, provocative look at breaking science. A former staff writer at Scientific American, he is the author of several books—most notably, The End of Science: Facing the Limits of Knowledge in the Twilight of the Scientific Age. He currently directs the Center for Science Writings at Stevens Institute of Technology. He lives in New York State's Hudson Highlands, where he plays ice hockey each winter to hone his cross-checking skills.

X

Expeditions Blog

Ever wonder what it's really like to be working in Antarctica or collecting core samples from the middle of the Pacific Ocean? Get a first-hand feel for scientific exploration by following the blog posts of researchers out in the field.

X

About the Extinction Countdown Blog

Several times a week, John Platt shines a light on endangered species from all over the globe, exploring not just why they are dying out but also what's being done to rescue them from oblivion. From unusual or little-known organisms like the giant spitting earthworm and the stinking hawk's-beard to popular favorites like cheetahs and koalas, Platt, a journalist specializing in environmental issues and technology, does his part to slow the countdown.

X

About the Guest Blog

The editors of Scientific American regularly encounter perspectives on science and technology that we believe our readers would find thought-provoking, fascinating, debatable and challenging. The guest blog is a forum for such opinions. The views expressed belong to the author and are not necessarily shared by Scientific American.

X

About the Solar at Home Blog

Follow Scientific American editor George Musser as he installs--or tries to install--solar photovoltaic panels on the roof of his suburban New Jersey home. You'll learn the literal nuts and bolts of going green with the sun and get energy-saving tips even if you aren't putting up panels.

Write to us with tips or comments at blog@sciam.com and follow us on Twitter: http://twitter.com/sciam.

X