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Jun 25, 2009
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For many women with breast cancer, tamoxifen, a drug that inhibits the hormone estrogen, can be a lifesaver.
The medicine has been used for decades to fight breast cancers that need estrogen to grow--about 75% of all breast cancers. Unfortunately, breast cancer cells can sometimes become resistant to tamoxifen, a dismal development for patients.
How do the cancer cells do it? Sherene Loi of the Peter MacCallum Cancer Centre in Australia is looking for the genes that underlie tamoxifen resistance.
Feb 19, 2009 | 1
In May 2001, Israeli parents of a nine-year old boy with a crippling disease that left him wheelchair-bound took their child to see doctors in Moscow. In a highly experimental procedure that was presumably unavailable in their home country, those doctors injected fetal stem cells into various regions of his brain.
The boy’s parents—they aren’t named in a report describing the case in this week’s PLoS Medicine—must have been desperate. The nine-year old suffered from ataxia-telangiectasia, a childhood disease that causes degeneration of parts of the brain that control muscle movements and speech. The symptoms include slurred speech, poor balance, impaired immune function, and the appearance of red spider veins called telangiectasias in the eyes, ears or cheeks.
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This challenge provides an opportunity for Solvers to build a web-based or mobile “app” to explore data relationships in scholarly conte
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Reward: $7,000 USD
The Seeker for this Challenge desires proposals for chemical methods that could rapidly degrade a dilute aqueous solution
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