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Postdoctoral Fellow, Clinical Cancer Sequencing Benchmarking

Employer: Ontario Institute for Cancer Research
Posted: January 7, 2014
Expires: November 5, 2014
Requisition number:

Science jobs from Ontario Institute for Cancer Research:
Position: Postdoctoral Fellow, Clinical Cancer Sequencing Benchmarking Site: MaRS Centre, Toronto Department: Informatics & Biocomputing Reports To: Dr. Paul C. Boutros Salary: Flexible based on experience Hours: 35 Hrs/week Status: Full-Time Contract, 1-3 years

Computational biology is driven by the development and application of improved tools and algorithms to difficult and important problems. But the comparison and optimization fo these tools is a critical and high-profile endeavour. The Boutros Lab research team at the Ontario Institute for Cancer Research specializes in this area, and is current leading multiple international benchmarking studies, including the ICGC-TCGA DREAM Somatic Mutation Calling Challenge (!Synapse:syn312572). This work is of the highest possible impact to the community, and is being very favourably reviewed and supported by journals throughout the world.

There is now the opportunity for a post-doctoral associate to lead benchmarking studies in the area of Clinical Cancer Sequencing. This includes execution and implementation of international Challenges, coordination with the two major cancer-sequencing consortia (ICGC & TCGA) and down-stream analysis of results to identify areas of need and to develop enhanced machine-learning techniques. This position calls for an engaged, ambitious PDF and has a strong chance of providing the contacts and publications to serve as a springboard towards an independent position. We have access to cutting-edge genomic data, associated with rich clinical annotation and a state-of-the-art IT infrastructure. All that's missing is the right candidate.

Preferred Qualifications PhD in computational biology, engineering, mathematics, computer science or a related field Experience with next-generation sequencing data required Strong programming skills (C, R, perl) preferrably in a linux-environment Strong statistical background (e.g. Bayesian or survival techniques) is an asset

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Research and Innovation.

For more information about OICR, please visit the website at

POSTED DATE: March 25, 2014 CLOSING DATE: Posted until filled

OICR has a diverse workforce and is an equal opportunity employer.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.

Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .doc file.

Don't forget to mention NatureJobs when applying.

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