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Postdoctoral Position of Gene Expression and / or Cancer Epigenetics

Employer: University of North Carolina at Chapel Hill
Posted: June 10, 2014
Expires: August 8, 2014
Requisition number:

Science jobs from University of North Carolina at Chapel Hill:
Multiple postdoctoral positions available for highly motivated candidates with a background in chromatin biology/epigenetics, biochemistry, and cancer cell biology to join UNC Lineberger Comprehensive Cancer Center and the Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill (UNC) School of Medicine. With an emphasis on chromatin biology and cancer epigenetics, the group focuses on mechanistic understandings of how chromatin modifications define the epigenome, control gene expression and regulate cell proliferation versus differentiation of tissue-specific stem cells during development, and how their deregulations lead to oncogenesis. Our recent research has contributed to a better understanding for various histone methylations and epigenetic factors, either chromatin-modifying enzymes or chromatin-associated factors, during the pathogenesis of human diseases, notably cancer Multiple on-going projects include 1) biochemical characterization of several novel chromatin-associated factors/complexes, 2) mouse models with deficiency in histone methylation regulation in context of development (hematopoiesis) or tumorigenesis, 3) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells, 4) shRNA or CRISPR-based screening for novel oncogenes or tumor suppressors.

Applicants, with a PHD or equivalent degree, should be self-motivated with a strong background, laboratory and analytical skills, as well as a track record of publication. Previous experiences in aforementioned fields are welcome but not required. Full applications including CV, a summary of research experiences, accomplishments and future interests, expected availability date, reprints of publications, and contact information of three referees should be submitted to e-mail:

UNC - Chapel Hill is an equal opportunity employer with a strong commitment to enhancing the diversity of its faculty and staff. Women and applicants from diverse racial, ethnic and cultural backgrounds are encouraged to apply.

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