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PhD Position


Employer: Otto-Von-Guericke University Magdeburg
Location:
Posted: June 13, 2014
Expires: July 25, 2014
Requisition number:

Science jobs from Otto-Von-Guericke University Magdeburg:
The Institute of Experimental Internal Medicine offers

PhD positions (m/f)

in an interdisciplinary project of Infection Biology.

Helicobacter pylori, the etiological agent of several human gastric diseases, induce the transcrip-tion factor NF-kB in colonized epithelial cells leading to the release of pro-inflammatory mediators. The project is based on recent discoveries of novel components of the NF-kB signaling pathway in mammalian cells. The successful applicants will define the role of this novel signaling molecules in Helicobacter pylori infection model by integrating molecular, physiological and cell biological analysis. The research program of the institute encompasses scientific projects on the regulation of the NF-kB signal transduction in the pathophysiology of inflammation and tumor biology (e.g. differentia-tion and cell cycle control). Here, the molecular and cell biological mechanisms of the intracellular signal transmission are of special interest. The institute allows an internationally competitive re-search by providing state of the art technologies in protein analysis, mass spectrometry and mi-croscopy. The institute coordinates and participates in a variety of coordinated programs funded by the Ger-man Research Foundation (GRK1167, SFB854, SFB779) and the Federal Ministry of Education and Research. Further, the institute is member of the interdisciplinary "Research Center Dynamic Systems: Bio-systems Engineering (CDS)" funded by the Federal State of Saxony-Anhalt within the "Excellence Program". The Otto von Guericke University wishes to increase the proportion of female academic person-nel. Women are therefore explicitly encouraged to apply. Handicapped persons with equivalent qualification will be given preference. Please send a motivation letter, CV and two references as PDF-file to Prof. M. Naumann (ieim@med.ovgu.de).

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