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PhD student / Doktorand


Employer: Ludwig-Maximilians Universitaet Muenchen, Germany
Location:
Posted: June 16, 2014
Expires: July 31, 2014
Requisition number:

Science jobs from Ludwig-Maximilians Universitaet Muenchen, Germany:
We are currently looking for a PhD student (with background in biology, molecular biology, medicinal chemistry, pharmaceutical sciences or similar) who would be interested in ion channel research, in particular in TRPML cation channels (mucolipins) and two-pore channels (TPCs). The candidate would ideally have experience in molecular biological techniques and experience in or have strong interest in patch-clamp electrophysiology and imaging techniques. The position is open for immediate occupation. The LMU is one of the top ranked German universities and our department is located on the LMU's high tech campus (Munich Grosshadern) with close proximity to several Max-Planck institutes and other research institutions. If you believe you fit this description then please send a brief letter of motivation, a short CV highlighting your academic and research accomplishments as well as copies of academic certificates and 3 recommendation letters to chgrph@cup.uni-muenchen.de. Dr. Dr. Christian Grimm Ludwig-Maximilians-Universität (LMU) München Department Pharmazie Center for Integrated Protein Science Munich (CIPSM) Butenandtstrasse 7 (Haus C, Raum 4.047A) 81377 München Tel.: 089/2180-77320 Fax: 089/2180-77326

Selected recent publications:

- Grimm, C., Jörs, S., Gao, Z., Obukhov, A.G., Heller, S. (2012b) Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules, J. Biol. Chem., 287:22701-22708 - Aneiros, E., Cao, L., Papakosta, M., Stevens, E.B., Phillips, S.C., Grimm, C. (2011) Biophysical and molecular basis of TRPV1 proton gating. EMBO J., 30:994-1002 - Grimm, C., Jörs, S., Saldanha, S.A., Obukhov, A.G., Pan, B., Oshima, K., Cuajungco, M.P., Chase, P., Hodder, P., Heller, S. (2010) Small molecule activators of TRPML3, Chem. & Biol. (Cell Press), 17:135-148 - Grimm, C., Jörs, S.*, Heller, S. (2009) Life and death of sensory hair cells expressing constitutively active TRPML3. J. Biol. Chem., 284:13823-13831 - Grimm, C., Cuajungco, M.P., van Aken, A.F.J., Schnee, M., Jörs, S., Kros, C.J., Ricci, A.J., and Heller, S. (2007) A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

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