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Post-Doctoral Fellowship


Employer: The Translational Genomics Research Institute (TGen)
Location:
Posted: August 4, 2014
Expires: October 3, 2014
Requisition number:

Science jobs from The Translational Genomics Research Institute (TGen):
The Translational Genomics Research Institute (TGen) is a nonā€profit biomedical research institute based in Phoenix, Arizona, focused on research that can help patients with cancer, neurological disorders, diabetes and other debilitating conditions. Working with a worldwide network of collaborators in the scientific and medical communities, TGen researchers study the genetic components of both common and complex diseases. Through genomic analysis, we learn how DNA, genes and proteins - the microscopic building block of life - can affect human health. Our 30 lead investigators and nearly 200 support personnel at sites in Phoenix, Scottsdale and Flagstaff, Arizona, are dedicated to improving patient care and quality of life through precision medicine, best defined as the right therapy, for the right patient, at the right time.

Job Summary TGen seeks a postdoctoral fellow for the Adrenocortical Carcinoma (ACC) unit. Rare cancers represent an understudied segment, but also afford development of translational research skills amenable to applications across other tumor types. Leveraging a unique collection of ACC cell lines and tumorgraft models, the Fellow will conduct studies to discover & develop targeted therapies. Research strategies include high throughput screening, genomic profiling, functional genomics, and ACC tissue microarrays, which will uncover targetable alterations responsible for ACC progression and metastasis. The project will identify novel drug treatment for ACC using cell line models and validate the finding in animal models. By closely working with clinicians at TGen's Clinical Research Service, the laboratory findings will be positioned for translation to clinical trials. Utilizing TGen's unique in vitro and in vivo tumor models, the Fellow will contribute to delivery of new therapeutics for clinical use against ACC. Fellows pursuing parallel studies at TGen on other solid tumors create a critical mass of team-science, each member bringing experience in tumor biology, high throughput screening, preclinical modeling, bioinformatics, and drug discovery & development aligned with genomic profiling for precision medicine. Career development opportunities for the Fellow include pharmaceutical company leadership, university/academic appointment, and program leadership at an independent research institute.

Job Qualification The successful candidate should be a PhD graduate with a strong background in molecular biology and/or biochemistry with a focus on cancer. The ideal candidate will exhibit flexibility, independence and creativity with a record of scientific productivity. Previous experience in cancer animal models is preferred.

To Apply If you are interested in applying for this position or learning more about TGen or benefits of working here, please go to http://careers.tgen.org. This is job# IRC9898. Only applications submitted through the TGen career website will be considered. If you have any questions, please contact Dr. Holly Yin hyin@tgen.org.

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