60-Second Science

Infecting Mosquitoes Before They Infect Us

A study in the journal Science shows that infecting disease-carrying mosquitoes with the bacteria Wolbachia could be an effective way to cut their lives--and infectious capacity--short. Cynthia Graber reports














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[The following is an exact transcript of this podcast.]

Mosquitoes carry nasty diseases—dengue fever, West Nile, malaria. But the microbes that cause those diseases don’t attach themselves to the mosquitoes and then immediately latch onto their next victim. They need time to grow and replicate in the mosquito before migrating to the bug’s salivary glands. For example, the dengue fever virus takes about two weeks to incubate.

So researchers from the University of Queensland in Australia and Central China Normal University are looking at a way to shorten the lives of mosquitoes—and thus curtail their disease-transmitting ability.

Researchers worked with a bacterial parasite called <i>Wolbachia</i> that infects numerous insect species. They spent three years adapting it to infect the Aedes aegypti mosquito, which carries dengue fever. It cut the lives of the mosquitoes by more than half. Those results were reported in the January 2nd issue of the journal <i>Science</i>. The scientists say that because <i>Wolbachia</i> shortens a mosquito’s life, the insects are that much less likely to pass on the diseases they carry. So a relatively inexpensive and effective human disease prevention program could be to mass-infect mosquitoes with <i>Wolbachia</i>. Which should make the medical community buzz.

—Cynthia Graber 

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  1. 1. abrasileirosilva 06:43 AM 1/2/09

    Nature.com has a good article about this theme (Bacteria could help control dengue fever, published online 31 December 2008), for now available. Yes, biotechnology helping us human beings; turning us from victims to hunters.

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  2. 2. Mythee 10:51 AM 1/2/09

    Mosquitoes have evolved within the ecosystem to have a certain lifespan. Would there be no consequences to shortening their lives, such as unavailability of mosquitoes to their predators at certain times, or a change in the rate of reproduction leading to overpopulation, or anything else? I love genetic engineering, but sometimes I feel that people are too hasty to apply concepts that could be harmful. Have there at least been controlled experiments with populations of mosquitoes to get an idea of whether there will be long term effects?

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  3. 3. abrasileirosilva 05:39 PM 1/3/09

    The BBC online (sections Health, or Science & Environment under the title "Bug could combat dengue fever" and dated of 2 January 2009) has a balanced presentation of the solution and of the problems related to this matter.

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