New Issue: Orbital Catastrophe Ahead? Read Now

HPV Vaccine Needs to Reach Boys, Too

Gypsyamber D’Souza of Johns Hopkins University discussed the rise in HPV-related oral cancer, its connection to oral sex and the risk for men at the annual meeting of the American Association for the Advancement of Science.

PhotoDisc/Getty Images (MARS)

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!

Human papillomavirus, or HPV, now causes the majority of tonsillar cancers in the United States and many western nations. And the risk of these cancers has been increasing.”

Gypsyamber D’Souza of Johns Hopkins University, February 12th at the annual meeting of the American Association for the Advancement of Science in Washington, DC.

“And it’s much higher in men than in women…we know performing oral sex is the main risk factor for oral HPV infection. And our research shows that performing oral sex is more common in younger generations than in previous generations. And that people are not only more likely to have performed oral sex but with more partners and to initiate it at any earlier age. And all of these differences in sexual behavior across age cohorts or generations do explain the differences that we see in oral HPV prevalence and in HPV-related oropharyngeal cancer across the generations and why the rate of this cancer is increasing...


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


“But differences in sexual behavior do not explain the differences that we see between men and women in oral HPV infection and HPV-related cancer…

“Men are not only more likely to become infected with oral HPV infection than women, but our research also showed that once you become infected, men are less likely to clear these infections than women. Further contributing to their cancer risk.”

Which means that it’s not just girls and women who should get the HPV vaccine.

“In terms of vaccination of boys, as a researcher who sees the patients with these cancers, the fact that there is a vaccine with great potential to prevent them is very compelling. Our vaccination rates have lagged in boys severely in the States, which is disappointing, but there is a lot of effort to improving that. And I think it’s quite an urgent public health issue to increase HPV vaccination in boys as well as girls.”

—Steve Mirsky

[The above text is a transcript of this podcast.]

Subscribe to Support Independent Journalism

Great science journalism requires human expertise, time, effort and creativity. And it costs money. That’s why I and the journalists here at Scientific American hope you’ll join our community.

When you subscribe, you are supporting staff and freelance journalists who are passionate about telling science stories that are true, important and compelling. Our editors and reporters are often experts in their fields, which means they understand the nuances of big discoveries and can untangle the breakthroughs from the hype. With a subscription, you are also supporting rigorous fact-checking to ensure the words we publish are precise and accurate. And you’re supporting original illustrations, graphics and photos that bring you closer to an advanced laboratory, an ice sheet in Antarctica or a space mission in orbit. You’re helping us craft other types of high-quality journalism as well: Our newsletters are carefully written, edited and curated by staffers you have or will come to know and love. Our Science Quickly podcast is based on original reporting, collaboration with editors and scientists and exacting production.

Subscriptions keep this engine running so we can continue to deliver thoughtful, rigorous and independent science journalism to you. In an era of viral misinformation, this work is crucial. If you value what we do, I hope you’ll consider joining us as a subscriber

Thank you,

Jeanna Bryner, Editor in Chief, Scientific American

Subscribe