Climate change skeptics have an arsenal of arguments for why humans need not cut their carbon emissions. Some assert rising CO2 levels benefit plants, so global warming is not as bad as scientists proclaim. “A higher concentration of carbon dioxide in our atmosphere would aid photosynthesis, which in turn contributes to increased plant growth,” Rep. Lamar Smith (R–Texas) wrote in an op-ed last year. “This correlates to a greater volume of food production and better quality food.” Scientists and others calling for emission cuts are being hysterical, he contends.

So is it true rising atmospheric CO2 will help plants, including food crops? Scientific American asked several experts to talk about the science behind this question.

There is a kernel of truth in this argument, experts say, based on what scientists call the CO2 fertilization effect. “CO2 is essential for photosynthesis,” says Richard Norby, a corporate research fellow in the Environmental Sciences Division and Climate Change Science Institute of Oak Ridge National Laboratory. “If you isolate a leaf [in a laboratory] and you increase the level of CO2, photosynthesis will increase. That’s well established.” But Norby notes the results scientists produce in labs are generally not what happens in the vastly more complex world outside; many other factors are involved in plant growth in untended forests, fields and other ecosystems. For example, “nitrogen is often in short enough supply that it’s the primary controller of how much biomass is produced” in an ecosystem, he says. “If nitrogen is limited, the benefit of the CO2 increase is limited…. You can’t just look at CO2, because the overall context really matters.”

Scientists have observed the CO2 fertilization effect in natural ecosystems, including in a series of trials conducted over the past couple decades in outdoor forest plots. In those experiments artificially doubling CO2 from pre-industrial levels increased trees’ productivity by around 23 percent, according to Norby, who was involved in the trials. For one of the experiments, however, that effect significantly diminished over time due to a nitrogen limitation. That suggests “we cannot assume the CO2 fertilization effect will persist indefinitely,” Norby says.

In addition to ignoring the long-term outlook, he says, many skeptics also fail to mention the potentially most harmful outcome of rising atmospheric CO2 on vegetation: climate change itself. Its negative consequences—such as drought and heat stress—would likely overwhelm any direct benefits that rising CO2 might offer plant life. “It’s not appropriate to look at the CO2 fertilization effect in isolation,” he says. “You can have positive and negative things going at once, and it’s the net balance that matters.” So although there is a basic truth to skeptics’ claim, he says, “what’s missing from that argument is that it’s not the whole picture.”

Scientists have also looked specifically at the effects of rising CO2 on agricultural plants and found a fertilization effect. “For a lot of crops, [more CO2] is like having extra material in the atmosphere that they can use to grow,” says Frances Moore, an assistant professor of environmental science and policy at the University of California, Davis. She and other experts note there is an exception for certain types of plants such as corn, which access CO2 for photosynthesis in a unique way. But for most of the other plants humans eat—including wheat, rice and soybeans—“having higher CO2 will help them directly,” Moore says. Doubling CO2 from pre-industrial levels, she adds, does boost the productivity of crops like wheat by some 11.5 percent and of those such as corn by around 8.4 percent.

A lack of nitrogen or other nutrients does not affect agricultural plants as much as wild ones, thanks to fertilizer. Still, research shows plants “get some benefits early on from higher CO2, but that [benefit] starts to saturate” after the gas reaches a certain level, Moore says—adding, “The more CO2 you have, the less and less benefit you get.” And while rising carbon dioxide might seem like a boon for agriculture, Moore also emphasizes any potential positive effects cannot be considered in isolation, and will likely be outweighed by many drawbacks. “Even with the benefit of CO2 fertilization, when you start getting up to 1 to 2 degrees of warming, you see negative effects,” she says. “There are a lot of different pathways by which temperature can negatively affect crop yield: soil moisture deficit [or] heat directly damaging the plants and interfering with their reproductive process.” On top of all that, Moore points out increased CO2 also benefits weeds that compete with farm plants.

Rising CO2’s effect on crops could also harm human health. “We know unequivocally that when you grow food at elevated CO2 levels in fields, it becomes less nutritious,” notes Samuel Myers, principal research scientist in environmental health at Harvard University. “[Food crops] lose significant amounts of iron and zinc—and grains [also] lose protein.” Myers and other researchers have found atmospheric CO2 levels predicted for mid-century—around 550 parts per million—could make food crops lose enough of those key nutrients to cause a protein deficiency in an estimated 150 million people and a zinc deficit in an additional 150 million to 200 million. (Both of those figures are in addition to the number of people who already have such a shortfall.) A total of 1.4 billion women of child-bearing age and young children who live in countries with a high prevalence of anemia would lose more than 3.8 percent of their dietary iron at such CO2 levels, according to Meyers.

Researchers do not yet know why higher atmospheric CO2 alters crops’ nutritional content. But, Myers says, “the bottom line is, we know that rising CO2 reduces the concentration of critical nutrients around the world,” adding that these kinds of nutritional deficiencies are already significant public health threats, and will only worsen as CO2 levels go up. “The problem with [the skeptics’] argument is that it’s as if you can cherry-pick the CO2 fertilization effect from the overall effect of adding carbon dioxide to the atmosphere,” Myers says. But that is not how the world—or its climate—works.