Elite memory athletes are not so different from their peers in any other sport: They face off in intense competitions where they execute seemingly superhuman feats such as memorizing a string of 500 digits in five minutes. Most memory athletes credit their success to hours of memorization technique practice. One lingering question, though, is whether memory champs succeed by practice alone or are somehow gifted. Recent research suggests there may be hope for the rest of us. A study, published today in Neuron, provides solid evidence that most people can successfully learn and apply the memorization techniques used by memory champions, while triggering large-scale brain changes in the process.

A team led by Martin Dresler at Radboud University in the Netherlands used a combination of behavioral tests and brain scans to compare memory champions with the general population. It found top memory athletes had a different pattern of brain connectivity than controls did, but also that subjects who learned a common memorization technique over a period of weeks, not years, greatly improved their memory skills, and began to exhibit brain connection patterns resembling those of elite memorizers.

Many of us learn new skills throughout our lives, and scientists have long wondered if and how our brains change as a result. Previous research has linked some skills to specific brain changes. One well-known set of studies showed that London taxi drivers developed more gray matter in their hippocampi (a brain area linked to memory) as they acquired the knowledge needed to navigate London’s haphazard maze of streets. Dresler and colleagues, motivated in part by co-author and professional memory trainer Boris Konrad, decided to focus on elite memory athletes who utilize memorization techniques to compete at highly specific tasks such as memorizing decks of cards or lines of binary digits in minutes. They wanted to know whether these highly skilled practitioners exhibit noticeable brain changes and how those changes occur.

In the first part of the study the researchers matched 23 elite memory champions with control subjects based on age, gender and IQ. Both groups underwent a series of brain scans including anatomical scans and functional magnetic resonance imaging (fMRI) during a resting state—one in which subjects were not doing anything—and during a memory task. The researchers found the memory champions did not differ from the controls in any particular brain region, but rather had different patterns of brain connectivity during resting-state and task-based fMRI scans. To Dresler, these results suggested “there’s not a sort of general hardware difference in memory champions that allows them to reach these memory levels but that something subtler is going on,” which spurred the team to investigate further.

Next, the researchers took 51 subjects who had never previously engaged in memory training and divided them into an experimental group and two control groups. Experimental subjects underwent six weeks of intense memory training for half an hour each day using the centuries-old method of loci strategy still popular with memory champions: They learned how to map new information such as numbers or names onto familiar spatial locations such as those in their homes. The active control group trained for a working memory task called the n-back that does not train long-term memory. Meanwhile the passive control group received no training.

After training, the experimental subjects improved significantly at memory tasks (whereas neither control group improved), yet did not exhibit any structural brain changes. Their brain connection patterns during resting state and task-based fMRI scans, however, became more similar to those of memory champs, a change that correlated positively with memory improvements. “I think the interesting part is that not only can you boost memory in a similar way behaviorally in normal subjects compared to memory athletes,” Dresler says, “but on the brain level you see a reflection of that behavioral increase, and you drive the brains of naive subjects into the patterns of the best memorizers in the world.”

James McGaugh, a neurobiologist at the University of California, Irvine, who was not involved in the study, considers it to be in a similar vein as the London taxi cab research, but highlights an important difference: Rather than pinpointing a particular brain region, the present study found an overall change in brain connections. “All of our brains are malleable all the time, and this is just another piece of evidence of that,” he says. “If you learn something and you learn it well, the brain changes.”

For his U.C. Irvine colleague, Craig Stark, a professor of neurobiology and behavior who also was not part the research, it represents “a really interesting contribution to the field.” Stark was particularly impressed by the study’s clever experimental design, which he expects to be adopted by researchers in other domains. He adds, the results align with the idea that our brains are highly plastic and continuously change and adapt. “This is showing that the act of going and learning something new is changing your brain, and changing the way you process things, which will change the way you actually see the world,” he says.