Annie, my friend John's kid sister, got sick when she was 11. I wasn't much older so I didn't know how serious it was when John said her disease was called lupus. I didn't realize her own cells were attacking her, sometimes going after her kidneys, other times her lungs. I did know, because her brother told me, that her face got really swollen because she had to take lots of pills called steroids, which had side effects that meant she could get very sick from flus or colds that he and I shrugged off. At times Annie missed long periods of school. At times she hurt badly. As she grew, she worked in children's theater, which she adored, and in local politics. Annie never got past lupus, though. She died at age 49.