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The Orphan Drug Backlash

The Orphan Drug Act of 1983 was supposed to provide incentives for private industry to develop needed, but unprofitable, drugs to treat rare diseases. It has done so, but not without eliciting controversy

By Thomas Maeder

The Iceman Reconsidered

Where was the Iceman's home and what was he doing at the high mountain pass where he died? Painstaking research--especially of plant remains found with the body--contradicts many of the initial speculations

By James H. Dickson, Klaus Oeggl and Linda L. Handley

Scale-Free Networks

Scientists have recently discovered that various complex systems have an underlying architecture governed by shared organizing principles. This insight has important implications for a host of applications, from drug development to Internet security

By Albert-László Barabási and Eric Bonabeau

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