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A Genome is Not a Blueprint

A Genome is Not a Blueprint

Image: 1936 Joy Oil gas station blueprints (top); sequence from human chromosome 1 (bottom). Source: from A Monkey’s Blueprint by Martin Krzywinski on SA Visual When artist Martin Krzywinski was challenged to come up with a graphic that quickly and concisely shows how the human genome is more similar to chimpanzee and bonobo genomes than [...]

August 27, 2014 — Kalliopi Monoyios

"Gene Drives" And CRISPR Could Revolutionize Ecosystem Management

A note from the authors: With this guest blog post we want to share the key features of an innovative method for the high-precision genome editing of wild populations that has been outlined by our team at the Wyss Institute, Harvard Medical School, and the Harvard School of Public Health.

July 17, 2014 — Kevin Esvelt, George Church and Jeantine Lunshof
FDA Was Right To Block 23andMe

FDA Was Right To Block 23andMe

A few techno-libertarians are up in arms over the FDA’s letter warning the genetics company 23andme to stop selling its personalized genome services kit.

November 25, 2013 — Christine Gorman

Using CRISPR to Do More Than Cut

Using the CRISPR–Cas9 system, scientists can do much more than gene editing—they can boost gene transcription or use fluorescent proteins to paint and track a chromosome. In this Nature Video animation, several innovative uses for CRISPR are outlined and explained. This video was reproduced with permission and was first published on October 31, 2017. It is a Nature Video production.

November 10, 2017 — Nature Video

NIH Begins Gene Therapy Trial for Parkinson’s Disease

All eyes were on Perry Cohen when he froze at the microphone. His voice failed him. He couldn’t read his notes. Eventually, the once-powerful Parkinson’s disease speaker had to be helped off the stage halfway through his speech.

July 26, 2013 — Dina Fine Maron
The Last Man on the Moon

The Last Man on the Moon

It’s no secret, I’m a space geek. And the other non-secret is I love when a good space travel book is turned into a movie. Astronaut Gene Cernan is known for being “The Last Man on the Moon” as he was the last man to walk on the moon during the Apollo 17 mission.

May 22, 2014 — Joanne Manaster
Hallmarks of Cancer 7: Genome Instability and Mutation

Hallmarks of Cancer 7: Genome Instability and Mutation

All cancers share ten underlying principles, also known as the Hallmarks of Cancer. You can read about the first six here. The seventh is defined as genome instability and mutation.

November 26, 2013 — Buddhini Samarasinghe
Genetic Engineering: Progress and Controversy

Genetic Engineering: Progress and Controversy

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this eBook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

November 5, 2018

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