Adulteration of Beer with Strychnine

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


Graham and Hoffman at the instance of a prominent English brewer, Mr. Alsopp, and in consequence of reports, originating in Paris, that English ale and beer' occasionally derived its bitterness from strychnine, have carefully tested various specimens of these beverages, but without discovering a trace of the poisonous alkaloid. St.-ychnine when present in no greater quantity than 1-1000 of a grain may be detected by the following process:— The suspected powder is to be moistened with a drop of undiluted sulphuric acid, and a few fragments of bichromate ot potash added. An intense beautiful violet color immediately appears at the points of contact which quickly spreads through the whole fluid, and after a few minutes again vanishes The presence of small quantities of organic matter prevents this reaction; in testing beer the authors adopted the following process :— Halt a gallon of beer to which one-half a grain of strychnine had been added was shaken with two ounces of animal charcoal, and the fluid allowed to stand over night. The next day the beer was found almost free from bitterness, the strychnine hiving been precipitated with the coal. The coal was thrown on a filter, washed, boiled with alcohol and the alcohoEc filtrate distilled. The residue in the retort was shaken with a few drops of a solution of caustic potash and about an ounce of ether. The etherial solution evaporated on a watch glass gave a mass in which the presence of strychnine was easily detected by the test above given.

Scientific American Magazine Vol 8 Issue 9This article was published with the title “Adulteration of Beer with Strychnine” in Scientific American Magazine Vol. 8 No. 9 (), p. 72
doi:10.1038/scientificamerican11131852-72e

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe