The above building was lately destroyed at a fire in Boston, by which the owner has been a great loser, but Mr. Chickering's loss is not to be measured by money: the patterns, the scales, and all the drawings, which have been the result of his long experience and close cal culations,—the work of many an evening hour of patient thought, have all been destroyed in 107 a night. One instrument in particular will be a great loss. For a year past Mr. Chickering has been engaged in planning and constructing a new piano, which would possess many ad. vantages over those now used in parlors. He had spent weeks and weeks upon its prepara tion, and had got it so far completed that in a day or two it would have been ready for ex hibition. This instrument, with all its pat terns and scales, is destroyed with the rest.