Scientists believe that random damage that occurs within cells and among extracellular molecules are responsible for many of the age-related changes that are observed in organisms.72,73,74 In addition, for organisms that reproduce sexually, including humans, each individual is genetically unique. As such, the rate of aging also varies from individual to individual.75 Despite intensive study, scientists have not been able to discover reliable measures of the processes that contribute to aging.76 For these reasons, any claim that a persons biological or "real age"77 can currently be measured, let alone modified, by any means must be regarded as entertainment, not science.
72Hayflick L. The Future of aging. Nature. 2000;408:267-269.
73Morley AA. The somatic mutation theory of ageing. Mut Res. 1995;338:19-23.
74Odagiri Y, Uchida H, Hosokawa M, Takemoto K, Morley A, Takeda T. Accelerated accumulation of somatic mutations in the senescence-accelerated mouse. Nat Genet. 1998;19:117-118.
75Carnes BA, Olshansky SJ. Heterogeneity and its biodemographic implications for longevity and mortality. Exp Gerontol. 2001;36:419-430.
76Workshop Report, Biomarkers of Aging: From Primitive Organisms to Man. International Longevity Center Canyon Ranch Series, New York, NY.; 2001.
77Roizen M. RealAge: Are you as young as you can be? Cliff Street Books; 1999.
78Roizen M, La Puma J. The RealAge diet: Make yourself younger with what you eat. Cliff Street Books; 2001.
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