By Eric Hand

As an engineer, Subra Suresh has made a career of studying stress and fatigue: from aluminum alloys in planes and silicon wafers in chips, to the walls of cells infected with malaria. As the man nominated by President Barack Obama's administration to head the U.S. National Science Foundation (NSF), Suresh may soon find himself as challenged as the materials in his lab, as the agency competes for cash in an increasingly austere budget climate.

The 54-year-old dean of engineering at the Massachusetts Institute of Technology (MIT) in Cambridge, Suresh was named on June 3 to lead the $6.9-billion NSF, which funds research in the non-medical sciences. If confirmed by the Senate, he would succeed nuclear engineer Arden Bement, who completed his six-year term at the end of May. Suresh--who would be the first Indian American to direct the NSF--would take over just as a $3-billion infusion of economic stimulus money given to the agency early last year begins to run out.

"Morale is going to be low," says Samuel Rankin, chair of the Coalition for National Science Funding, an advocacy group based in Washington, D.C. "He needs to take advantage of the fact that he's new and push for more funding."

Suresh studied mechanical engineering at the Indian Institute of Technology Madras in Chennai and received a doctorate from MIT in 1981. His research career has ranged widely, from the macroscopic study of alloys to the microscopic study of thin films such as those used in silicon chips. Now, he focuses on the biomechanics of diseased human cells. Colleagues say he has tried to foster such interdisciplinary work at MIT, and has boosted the number of researchers who hold joint appointments at two departments.

"Usually interdisciplinary means non-disciplinary," says Ben Freund, a mechanical engineer at Brown University in Providence, R.I., who in 1983 recruited Suresh as an assistant professor there. "But he's truly made himself proficient in a number of areas and joined them in ways that have had an impact."

Ares Rosakis, who met Suresh as a graduate student at Brown, sees similarities between Suresh and another U.S. agency head: Steven Chu at the Department of Energy. Like Chu, Rosakis says, Suresh is an academic shape-shifter who enthusiastically devours new topics. And, like Chu, who directed the Lawrence Berkeley National Laboratory in California before he came to the capital, Suresh has maintained an active research lab after becoming an administrator. "You have to share some of the excitement of the process of research in order to actually implement the right changes," says Rosakis, now an aerospace and mechanical engineer at the California Institute of Technology in Pasadena.

In another parallel with Chu, Suresh will arrive in Washington, D.C., as a relative newcomer. "He may not have as much policy experience in Washington as some of his predecessors have had," says Eric Grimson, who works with Suresh as head of MIT's Department of Electrical Engineering and Computer Science. But Suresh has proved himself adroit at securing backing from fellow academics for endeavors such as revamping the engineering curriculum at MIT, his colleagues say. "I have no idea if his exposure to politics is enough," says Rosakis. "But academic politics can be very nasty too."

If confirmed, Suresh is likely to encounter politics in spades. The stimulus funding that was a windfall for the NSF last year came alongside a whopping 6.2 percent rise in regular agency funding for fiscal year 2010. As a result, the NSF made a record number of research grants, using stimulus funds to boost the acceptance rate for a backlog of qualified proposals. But that rate will drop as the stimulus money peters out, says Rankin.

Congress is unlikely to set the NSF's budget until after the midterm elections in November, which means funding could be frozen at 2010 levels well into next year. With concerns about the national debt rising, observers say that when Congress does act, the agency will be lucky to get half of the 8 percent budget increase that was requested by the White House in February.