Leech Therapy Quells the Aches and Pains of Osteoarthritis

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Though it might sound like an oxymoron, leech therapy may well succeed where other treatments fail in providing relief for the pain and inflammation of osteoarthritis, according to a new study. The findings appear in the current issue of the Annals of the Rheumatic Diseases.

In fact, leeches once were commonly used for pain relief, but fell out of favor last century. To assess the efficacy of the old-fashioned approach, Andreas Michalsen of the Essen-Mite Clinic in Essen, Germany, and colleagues conducted a pilot study involving 16 patients who had had knee pain for more than six months. X-rays revealed telltale signs of osteoarthritis in all of the participants, whose average age was 68. In addition to the exercise, physiotherapy, relaxation therapy and dietary changes the subjects had already incorporated into their treatment regimen, ten patients received leech therapy for the pain. This involved placing four medicinal leeches on the inflamed knee and leaving them there for 80 minutes. The other six patients were given conventional pain treatment.

The researchers recorded pain levels three days prior to starting pain treatment and 28 days after treatment had finished. Although the initial leech bite proved slightly painful to some of the patients, the therapy brought significant pain relief within 24 hours. The alleviation continued four weeks later, without side effects or infections. Those participants who received conventional treatment, in contrast, did not report pain relief.


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As to why these reviled creatures might have such soothing effects, the authors note that leech saliva contains various analgesic, anaesthetic and histamine-like compounds. Despite the small size of their study, the researchers say, their results indicate that leech therapy deserves further study

Kate Wong is an award-winning science writer and senior editor for features at Scientific American, where she has focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for nearly 30 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home to the shores of Kenya’s Lake Turkana in search of the oldest stone tools in the world, as well as to Madagascar on an expedition to unearth ancient mammals and dinosaurs, the icy waters of Antarctica, where humpback whales feast on krill, and a “Big Day” race around the state of Connecticut to find as many bird species as possible in 24 hours. Wong is co-author, with Donald Johanson, of Lucy’s Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow her on Bluesky @katewong.bsky.social

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