With the death of biologist E. O. Wilson on Sunday, I find myself again reflecting on the complicated legacies of scientists whose works are built on racist ideas and how these ideas came to define our understanding of the world.

After a long clinical career as a registered nurse, I became a laboratory-trained scientist as researchers mapped the first draft of the human genome. It was during this time that I intimately familiarized myself with Wilson’s work and his dangerous ideas on what factors influence human behavior.

His influential text Sociobiology: The New Synthesis contributed to the false dichotomy of nature versus nurture and spawned an entire field of behavioral psychology grounded in the notion that differences among humans could be explained by genetics, inheritance and other biological mechanisms. Finding out that Wilson thought this way was a huge disappointment, because I had enjoyed his novel Anthill, which was published much later and written for the public.

Wilson was hardly alone in his problematic beliefs. His predecessors—mathematician Karl Pearson, anthropologist Francis Galton, Charles Darwin, Gregor Mendel and others—also published works and spoke of theories fraught with racist ideas about distributions of health and illness in populations without any attention to the context in which these distributions occur.

Even modern geneticists and genome scientists struggle with inherent racism in the way they gather and analyze data. In his memoir A Life Decoded: My Genome: My Life, geneticist J. Craig Venter writes, “The complex provenance of ideas means their origin is often open to interpretation.”

To put the legacy of their work in the proper perspective, a more nuanced understanding of problematic scientists is necessary. It is true that work can be both important and problematic—they can coexist. Therefore it is necessary to evaluate and critique these scientists, considering, specifically the value of their work and, at the same time, their contributions to scientific racism.

First, the so-called normal distribution of statistics assumes that there are default humans who serve as the standard that the rest of us can be accurately measured against. The fact that we don’t adequately take into account differences between experimental and reference group determinants of risk and resilience, particularly in the health sciences, has been a hallmark of inadequate scientific methods based on theoretical underpinnings of a superior subject and an inferior one. Commenting on COVID and vaccine acceptance in an interview with PBS NewsHour, recently retired director of the National Institutes of Health Francis Collins pointed out, “You know, maybe we underinvested in research on human behavior.”

Second, the application of the scientific method matters: what works for ants and other nonhuman species is not always relevant for health and/or human outcomes. For example, the associations of Black people with poor health outcomes, economic disadvantage and reduced life expectancy can be explained by structural racism, yet Blackness or Black culture is frequently cited as the driver of those health disparities. Ant culture is hierarchal and matriarchal, based on human understandings of gender. And the descriptions and importance of ant societies existing as colonies is a component of Wilson’s work that should have been critiqued. Context matters.

Lastly, examining nurture versus nature without any attention to externalities, such as opportunities and potential (financial structures, religiosity, community resources and other societal structures), that deeply influence human existence and experiences is both a crude and cruel lens. This dispassionate query will lead to individualistic notions of the value and meaning of human lives while, as a society, our collective fates are inextricably linked.

As we are currently seeing in the COVID-19 pandemic, public health and prevention measures are colliding with health services delivery and individual responsibility. Coexistence of approaches that take both of these  into account are interrelated and necessary.

So how do we engage with the problematic work of scientists whose legacy is complicated? I would suggest three strategies to move toward a more nuanced understanding of their work in context.

First, truth and reconciliation are necessary in the scientific record, including attention to citational practices when using or reporting on problematic work. This approach includes thinking critically about where and when to include historically problematic work and the context necessary for readers to understand the limitations of the ideas embedded in it. This will require commitments from journal editors, peer reviewers and the scientific community to invest in retrofitting existing publications with this expertise. They can do so by employing humanities scholars, journalists and other science communicators with the appropriate expertise to evaluate health and life sciences manuscripts submitted for publication.

Second, diversifying the scientific workforce is crucial not only to asking new types of research questions and unlocking new discoveries but also to conducting better science. Other scholars have pointed out that feminist standpoint theory is helpful in understanding white empiricism and who is eligible to be a worthy observer of the human condition and our world. We can apply the same approach to scientific research. All of society loses when there are limited perspectives that are grounded in faulty notions of one or another group of humans’ potential. As my work and that of others have shown, the people most burdened by poor health conditions are more often the ones trying to address the underlying causes with innovative solutions and strategies that can be scientifically tested.

Finally, we need new methods. One of the many gifts of the Human Genome Project was the creativity it spawned beyond revealing the secrets of the genome, such as new rules about public availability and use of data. Multiple labs and trainees were able to collaborate and share work while establishing independent careers. New rules of engagement emerged around the ethical, legal and social implications of the work. Undoing scientific racism will require commitments from the entire scientific community to determine the portions of historically problematic work that are relevant and to let the scientific method function the way it was designed—to allow for dated ideas to be debunked and replaced.

The early work of Venter and Collins was foundational to my dissertation, which examined tumor markers of ovarian cancer. I spent time during my training at the NIH learning from these iconic clinicians and scholars and had occasion to meet and question both of them. As a person who uses science as one of many tools to understand the world, it is important to remain curious in our work. Creative minds should not be resistant to change when rigorous new data are presented. How we engage with old racist ideas is no exception.