The COVID-19 Postscript

A surprising number of COVID-recovered patients deal with an array of troublesome symptoms, well after the disease is gone

Scientific American Health & Medicine, Vol. 3, Issue 2

Scientific American Health & Medicine, Vol. 3, Issue No. 2

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


In the early months of the COVID-19 outbreak individuals took to social media to connect with others who, like them, were experiencing a wide array of problems long after they’d recovered from the disease itself. Symptoms included lingering fatigue, shortness of breath, “brain fog” and recurring fevers. In the year since it was officially declared a pandemic, SARS-CoV-2, the coronavirus that causes COVID, has sickened or infected more than 100 million people worldwide and killed more than 2.5 million. And it leaves an insidious postscript: a vague collection of ailments that can persist for weeks, sometimes months, even in patients who experienced only mild symptoms. Some epidemiologists, writes physician Carolyn Barber, estimate that at the end of the pandemic we may have some five million COVID “long haulers” (see “The Problem of ‘Long-Haul’ COVID”).

Particularly troubling, reports writer Stefani Sutherland, are neurological impacts of the virus that disrupt synaptic connections and interfere with brain function, affecting speech and upping the incidence of depression, anxiety and sleep disorders (see “COVID Can Cause Forgetfulness, Mania or a Stutter”). The good news is that vaccinations are well underway and will help curb viral transmission. But assessing, researching and ameliorating the consequences of the virus will be ongoing for a long time.

Andrea Gawrylewski is chief newsletter editor at Scientific American. She writes the daily Today in Science newsletter and oversees all other newsletters at the magazine. In addition, she manages all special editions and in the past was the editor for Scientific American Mind, Scientific American Space & Physics and Scientific American Health & Medicine. Gawrylewski got her start in journalism at the Scientist magazine, where she was a features writer and editor for "hot" research papers in the life sciences. She spent more than six years in educational publishing, editing books for higher education in biology, environmental science and nutrition. She holds a master's degree in earth science and a master's degree in journalism, both from Columbia University, home of the Pulitzer Prize.

More by Andrea Gawrylewski
SA Health & Medicine Vol 3 Issue 2This article was published with the title “The COVID-19 Postscript” in SA Health & Medicine Vol. 3 No. 2 ()
doi:10.1038/scientificamerican042021-3VFE7aX6P3UtjkiBJjMULX

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe