To Coagulate Blood

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


A new process has been lately invented by Dr. Pravaz, of Lyons, for coagulating the blood in the arteries, which he proposes to apply to the healing of aneurisms. The operation consists in injecting into the arteries a few drops of the perchloride of iron in its most concentrated state. The injection is effected by introducing a very fine trocar of gold or platina obliquely through the coats of the artery, to which a syringe is adapted. It is necessary to stop for the time the circulation in the artery. Of the three experimen+t noticed in the account made by the discover or to the French Academy of Sciences, the first was performed on a full grown sheep; the carotid artery having been exposed, the circulation was interrupted by pressure of the thumb and finger at two points an inch and a half distant, intercepting about ? spoonful of blood; a few drops of the styptic were then injected by the means above indicated. Immediately alter the operation an increased density of-the blood was perceptible to the touch; the rapid formation of the clot or co-agulum could be felt. Alter the lapse of four minutes the compression was removed; at the end of eight days the mass of curdled blood had not been driven from its position by the impulsion of the arterial blood. The two other experiments tried on horses confirmed the satisfactory conclusions drawn from the success of the first. Dr. Pravaz finds that about two drops of the perchloride of iron are requisite to the coagulation of a teaspoonful of blood. In applying the process to aneurisms, he would inject the percolorid e into the aneu-rismal cyst, after arresting the circulation by compression of the artery beyond the tumor, that is between it and the capillary vessels, in this way a compact clot of curdled blood may, he thinks, be found, acting like a cork to obstruct the artery and producing-the effect of a ligature.

Scientific American Magazine Vol 8 Issue 25This article was published with the title “To Coagulate Blood” in Scientific American Magazine Vol. 8 No. 25 (), p. 193
doi:10.1038/scientificamerican03051853-193

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe