Tobacco Hornworm Experiences Love at First Bite

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For most people, discriminating among foods is a luxury¿filet mignon is great, but rice and beans will do. For the tobacco hornworm, however, following one's dietary preferences is a matter of life or death. Indeed, research published in the current issue of the journal Nature shows that the larvae of this moth can become so chemically dependent on their favorite plants that they will starve to death rather than eat anything else.

To examine hornworm feeding preferences, Marta L. del Campo of the State University of New York at Binghamton and her colleagues raised the larvae on either of two diets. The first group was fed only the leaves of solanaceous plants¿potato and other members of the nightshade family; the second group grew up eating non-solanaceous plants. Switching the insects from one regimen to the other yielded interesting results: whereas larvae reared on non-solanaceous diets happily feasted on the nightshade foliage, most of those brought up on nightshade leaves flatly refused the foreign food and died of starvation. "When the hornworm larva feeds on plants from the nightshade family, its taste receptors become tuned to the plant chemical Indioside D, a steroidal glycoside compound that is made of a steroid unit and the sugars glucose, rhamnose and galactose," del Campo explains. "The receptors increase their responsiveness to this chemical, while maintaining low responses to other plant compounds."

Though it might seem maladaptive, the hornworm larvae's addiction to solanaceous leaves can pay off: larvae raised on nightshade plants¿the insect's natural hosts¿mature far more quickly than those reared on non-solanaceous foliage. As a result they spend less time in the vulnerable larval stage. At the same time, however, adult females occasionally lay their eggs on non-host plants. It thus pays for hornworm larvae to have the potential to become either specialists or generalists, depending on what food is first available to them.

Kate Wong is an award-winning science writer and senior editor for features at Scientific American, where she has focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for nearly 30 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home to the shores of Kenya’s Lake Turkana in search of the oldest stone tools in the world, as well as to Madagascar on an expedition to unearth ancient mammals and dinosaurs, the icy waters of Antarctica, where humpback whales feast on krill, and a “Big Day” race around the state of Connecticut to find as many bird species as possible in 24 hours. Wong is co-author, with Donald Johanson, of Lucy’s Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow her on Bluesky @katewong.bsky.social

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