Use It or Lose It


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It is a question that has long befuddled evolutionary biologists. Why do populations of organisms become specialized? Take cave fish, for example. These creatures, which dwell in perpetual darkness, are generally blind, having either greatly reduced eyes or no eyes at all. Yet presumably they evolved from fish with functioning eyes. Granted, vision doesn¿t help in the cave environment, but why ¿lose¿ the ability to survive in other niches? Researchers have put forth two theories. One holds that unused functions can accumulate destructive mutations without affecting the creature. The other theory posits that unused functions get dropped in order to redirect the energy involved in maintaining them, enhancing useful functions. New research published in the journal Nature supports the latter idea.

In order to address this question, researchers at Michigan State University decided to simulate evolution in the lab. They raised 12 strains of E. coli bacteria on glucose alone to see whether they would lose their ability to process other sugars. Twenty thousand generations later, the team found that indeed they had. Moreover, it seems that the bacteria lost their ability to grow on other sugars because doing so made them more efficient glucose-eaters¿a mechanism dubbed antagonistic pleiotropy. Natural selection thus appears, at least according to this study, to favor dumping extraneous functions in order to focus on what¿s useful.

Kate Wong is an award-winning science writer and senior editor at Scientific American focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for more than 25 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home, to the shores of Kenya's Lake Turkana in search of the oldest stone tools in the world, to Madagascar on an expedition to unearth ancient mammals and dinosaurs, to the icy waters of Antarctica, where humpback whales feast on krill, and on a "Big Day" race around the state of Connecticut to find as many bird species as possible in 24 hours. Kate is co-author, with Donald Johanson, of Lucy's Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow Wong on X (formerly Twitter) @katewong

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