What Is It? Fraying Matter

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


This lacelike pattern is made from a hard substance that has turned as fragile as fabric. Norman Barker, an associate professor of pathology and art as applied to medicine at Johns Hopkins University, took this photograph of the femur of a woman between the ages of 45 and 50 with osteoporosis. It shows cancellous, or spongy, bone, the network of interconnected spicules that form inside a bone’s stronger outer layers. Cancellous bone provides the framework on which bone marrow cells grow and also makes essential minerals available to the body. In osteoporosis, the spaces between the spicules start to get bigger, “and this awakening of the bone leads to fractures,” Barker says. Using new software tools, he stitched multiple images together to create an unlimited depth of focus for a better look at how osteo­porosis ravages the body. “This type of image would have been impossible to capture just a couple of years ago,” Barker notes.

Scientific American Magazine Vol 304 Issue 6This article was published with the title “What Is It? Fraying Matter” in Scientific American Magazine Vol. 304 No. 6 ()
doi:10.1038/scientificamerican062011-2ZwJISRLD9op7Uxk9Dgr3h

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe