HIV drugs turned street drugs in South Africa

Join Our Community of Science Lovers!

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American



On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


Teens in South Africa have found a new use for efavirenz (brand name Stocrin in South Africa and Sustiva in the U.S.), an antiretroviral drug that prevents HIV from making copies of itself in the body. Instead of using efavirenz as it was intended – to keep the AIDS virus at bay – kids are crushing the pills and smoking the powder to get high, ABC News reports.

When taken as prescribed, efavirenz can cause side effects, including drowsiness and vivid, colorful dreams, but when smoked, it induces hallucinations and is highly addictive. "Once you've first started, there's no turning back," a 17-year-old addict told ABC News.

Krista Dong, an infectious disease specialist and internist at Edendale Hospital in South Africa’s KwaZulu Natal province, tells ScientificAmerican.com that the abuse of efavirenz is nothing new.

"It was first reported at least one and a half years ago," she says, noting that the trend has led to stricter oversight of efavirenz in hospitals, which in turn has caused delays in delivering the drug to patients in need. Before efavirenz had any street value, nurses wheeling drug carts through the hospital dispensed it to HIV/AIDS patients, but now the drug is locked it away in the hospital's main pharmacy, seven floors below the ward, Dong explains. For nurses who may be caring for as many as 40 extremely ill patients at a time, making special trips to this pharmacy costs precious time, she adds.

As for HIV patients being treated with efavirenz outside the hospital, "they are in danger of being robbed for these medications," according to Zinhle Thabethe, an HIV counselor at Edendale. Thabethe says that teenagers sometimes steal the drug from their ailing parents to get high. 

Image © iStockphoto/kWaiGon

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe