HIV drugs turned street drugs in South Africa

Join Our Community of Science Lovers!

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American



On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


Teens in South Africa have found a new use for efavirenz (brand name Stocrin in South Africa and Sustiva in the U.S.), an antiretroviral drug that prevents HIV from making copies of itself in the body. Instead of using efavirenz as it was intended – to keep the AIDS virus at bay – kids are crushing the pills and smoking the powder to get high, ABC News reports.

When taken as prescribed, efavirenz can cause side effects, including drowsiness and vivid, colorful dreams, but when smoked, it induces hallucinations and is highly addictive. "Once you've first started, there's no turning back," a 17-year-old addict told ABC News.

Krista Dong, an infectious disease specialist and internist at Edendale Hospital in South Africa’s KwaZulu Natal province, tells ScientificAmerican.com that the abuse of efavirenz is nothing new.

"It was first reported at least one and a half years ago," she says, noting that the trend has led to stricter oversight of efavirenz in hospitals, which in turn has caused delays in delivering the drug to patients in need. Before efavirenz had any street value, nurses wheeling drug carts through the hospital dispensed it to HIV/AIDS patients, but now the drug is locked it away in the hospital's main pharmacy, seven floors below the ward, Dong explains. For nurses who may be caring for as many as 40 extremely ill patients at a time, making special trips to this pharmacy costs precious time, she adds.

As for HIV patients being treated with efavirenz outside the hospital, "they are in danger of being robbed for these medications," according to Zinhle Thabethe, an HIV counselor at Edendale. Thabethe says that teenagers sometimes steal the drug from their ailing parents to get high. 

Image © iStockphoto/kWaiGon

Subscribe to Support Independent Journalism

Great science journalism requires human expertise, time, effort and creativity. And it costs money. That’s why I and the journalists here at Scientific American hope you’ll join our community.

When you subscribe, you are supporting staff and freelance journalists who are passionate about telling science stories that are true, important and compelling. Our editors and reporters are often experts in their fields, which means they understand the nuances of big discoveries and can untangle the breakthroughs from the hype. With a subscription, you are also supporting rigorous fact-checking to ensure the words we publish are precise and accurate. And you’re supporting original illustrations, graphics and photos that bring you closer to an advanced laboratory, an ice sheet in Antarctica or a space mission in orbit. You’re helping us craft other types of high-quality journalism as well: Our newsletters are carefully written, edited and curated by staffers you have or will come to know and love. Our Science Quickly podcast is based on original reporting, collaboration with editors and scientists and exacting production.

Subscriptions keep this engine running so we can continue to deliver thoughtful, rigorous and independent science journalism to you. In an era of viral misinformation, this work is crucial. If you value what we do, I hope you’ll consider joining us as a subscriber

Thank you,

Jeanna Bryner, Editor in Chief, Scientific American

Subscribe